Publications by Radiana Ferrero

A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion

Bart Deplancke, Vincent Roland Julien Gardeux, Julie Marie Russeil, Jörn Pezoldt, Guido Van Mierlo, Daniel Alpern, Pernille Yde Rainer, Magda Zachara, Radiana Ferrero

Although several mouse and human adipose SVF cellular subpopulations have by now been identified, we still lack an understanding of the cellular and functional variability of adipose stem and progenitor cell (ASPC) populations across human fat depots. To a ...

Cell Press2024

Cross-anatomical single-cell definition and characterization of human adipose progenitor niche

Radiana Ferrero

Adipose tissue is a key metabolic and highly-dynamic organ whose dysregulation may cause clinical conditions of concern such as obesity and lipodystrophy. Its function varies based on the anatomy, in fact, visceral adipose tissue expansion carries a greate ...

EPFL2023

Mammalian adipogenesis regulator (Areg) cells use retinoic acid signalling to be non- and anti-adipogenic in age-dependent manner

Bart Deplancke, Julie Marie Russeil, Horia Hashimi, Daniel Alpern, Maria Litovchenko, Magda Zachara, Pernille Yde Rainer, Radiana Ferrero

Adipose stem and precursor cells (ASPCs) give rise to adipocytes and determine the composition and plasticity of adipose tissue. Recently, several studies have demonstrated that ASPCs partition into at least three distinct cell subpopulations, including th ...

WILEY2022

Toward a Consensus View of Mammalian Adipocyte Stem and Progenitor Cell Heterogeneity

Bart Deplancke, Pernille Yde Rainer, Radiana Ferrero

White adipose tissue (WAT) is a cellularly heterogeneous endocrine organ that not only serves as an energy reservoir, but also actively participates in metabolic homeostasis. Among the main constituents of adipose tissue are adipocytes, which arise from ad ...

ELSEVIER SCIENCE LONDON2020