Hatice Altug

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Chirality encoding in resonant metasurfaces governed by lattice symmetries

Chiral metasurfaces provide invaluable tools for controlling structured light required for biosensing, photochemistry, holography, and quantum photonics. Here we suggest and realize a universal strategy for engineering chiral response of resonant metasurfa ...

Springer Science and Business Media LLC2025

Magnesium Optrodes for Real-Time Optical Monitoring of Water Transport in Ultrathin Encapsulations for Bioelectronics

Yves Leterrier, Stéphanie Lacour, Hatice Altug, Deepthy Kavungal, Massimo Mariello

Recent studies investigated the hydrolysis of Magnesium (Mg) thin films, highlighting their potential use in biodegradable devices. Quantitatively monitoring the degradation rate and morphological changes of Mg through optical methods and light-delivery de ...

2024

Bioinspired Three-Component System to Prepare Full-Color Functional Biomimetic Pigments

Hatice Altug

Nature provides a great source of inspiration for the development of sustainable materials with excellent properties, among which melanin with optical, electronic, and radiation protection properties are considered to be promising coloring materials. Howev ...

AMER CHEMICAL SOC2024

Long-Term and Continuous Plasmonic Oligonucleotide Monitoring Enabled by Regeneration Approach

Hatice Altug, Saeid Ansaryan

The demand for continuous monitoring of biochemical markers for diagnostic purposes is increasing as it overcomes the limitations of traditional intermittent measurements. This study introduces a method for long-term, continuous plasmonic biosensing of oli ...

Wiley-VCH Verlag GmbH2024

Continuous Biosensing to Monitor Acute Systemic Inflammation, a Diagnostic Need for Therapeutic Guidance

Hatice Altug

Continuous monitoring of acute inflammation can become a very important next step for guiding therapeutic interventions in severely ill patients. This Perspective discusses the current medical need for patients with acute inflammatory diseases and the pote ...

AMER CHEMICAL SOC2024

Deep learning augmented nanoplasmonic infrared sensor for structural protein biomarker-based detection of neurodegenerative diseases

Hilal Lashuel, Hatice Altug, Deepthy Kavungal, Rajasekhar Kolla, Pedro José Santana Ribeiro Magalhães

We introduce an infrared metasurface sensor based on plasmonic surface-enhanced infrared absorption spectroscopy combined with immunoassay, which detects alpha-synuclein, an early structural biomarker protein for neurodegenerative diseases with clinical sp ...

SPIE2024

Optical biosensors towards the clinic

Hatice Altug

Nature Photonics spoke with Hatice Altug, from the & Eacute;cole Polytechnique F & eacute;d & eacute;rale de Lausanne (EPFL), Thomas Krauss, from the University of York, and Malini Olivo from the Agency for Science, Technology and Research (A*STAR) about o ...

Nature Publishing Group2024

Gradient High-Q Dielectric Metasurfaces for Broadband Sensing and Control of Vibrational Light-Matter Coupling

Hatice Altug, Felix Ulrich Richter, Aleksandrs Leitis

Surface-enhanced infrared absorption spectroscopy (SEIRA) has emerged as a powerful technique for ultrasensitive chemical-specific analysis. SEIRA can be realized by employing metasurfaces that can enhance light-matter interactions in the spectral bands of ...

Wiley-V C H Verlag Gmbh2024

Stepwise release of Activin-A from its inhibitory prodomain is modulated by cysteines and requires furin coexpression to promote melanoma growth

Hatice Altug, Daniel Constam, Benjamin Marcel Daniel Rothé, Saeid Ansaryan, Pierpaolo Ginefra, Manon Bulliard, Céline Emmanuelle Schmuziger, Katarina Pinjusic

The Activin-A precursor dimer can be cleaved by furin, but how this proteolytic maturation is regulated in vivo and how it facilitates access to signaling receptors is unclear. Here, analysis in a syngeneic melanoma grafting model shows that without furin ...

2024

Challenges and perspectives of CRISPR-based technology for diagnostic applications

Hatice Altug

The precision and versatility of CRISPR-based techniques, combined with the advantages of nucleic acid-based nanotechnology, hold great promise in transforming the landscape of molecular diagnostics. While significant progress has been made, current CRISPR ...

Elsevier Sci Ltd2024

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Magnesium Optrodes for Real-Time Optical Monitoring of Water Transport in Ultrathin Encapsulations for Bioelectronics

Yves Leterrier, Stéphanie Lacour, Hatice Altug, Deepthy Kavungal, Massimo Mariello

2024

Stepwise release of Activin-A from its inhibitory prodomain is modulated by cysteines and requires furin coexpression to promote melanoma growth

Hatice Altug, Daniel Constam, Benjamin Marcel Daniel Rothé, Saeid Ansaryan, Pierpaolo Ginefra, Manon Bulliard, Céline Emmanuelle Schmuziger, Katarina Pinjusic

2024

Deep learning augmented nanoplasmonic infrared sensor for structural protein biomarker-based detection of neurodegenerative diseases

Hilal Lashuel, Hatice Altug, Deepthy Kavungal, Rajasekhar Kolla, Pedro José Santana Ribeiro Magalhães

SPIE2024