Person
Giorgio Elikem Tamo
This person is no longer with EPFL
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Related publications (6)
Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.
The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain
Matteo Dal Peraro, Maria Josefina Marcaida Lopez, Giorgio Elikem Tamo, Ruedi Aebersold
The polyQ expansion in huntingtin protein (HTT) is the prime cause of Huntington's disease (HD). The recent cryoelectron microscopy (cryo-EM) structure of HTT-HAP40 complex provided the structural information on its HEAT-repeat domains. Here, we present an ...
CELL PRESS2020A further leap of improvement in tertiary structure prediction in CASP13 prompts new routes for future assessments
Matteo Dal Peraro, Luciano Andres Abriata, Giorgio Elikem Tamo
We present our assessment of tertiary structure predictions for hard targets in Critical Assessment of Structure Prediction round 13 (CASP13). The analysis includes (a) assignment and discussion of best models through scores-aided visual inspection of mode ...
WILEY2019Constrained optimization applied to multiscale integrative modeling
Multiscale integrative modeling stands at the intersection between experimental and computational techniques to predict the atomistic structures of important macromolecules. In the integrative modeling process, the experimental information is often integra ...
EPFL2018