Ye Yang

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pH-Mediated molecular differentiation for fluorimetric quantification of chemotherapeutic drugs in human plasma

Francesco Stellacci, Stefan Guldin, Ye Yang

Royal Society of Chemistry2018

Structure-Property Relationships of Amphiphilic Nanoparticles That Penetrate or Fuse Lipid Membranes

Francesco Stellacci, Davide Demurtas, Paulo Henrique Jacob Silva, Randy Patrick Carney, Ye Yang, Ahmet Bekdemir, Zekiye Pelin Güven

2018

High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry

Francesco Stellacci, Ahmet Bekdemir, Li Tang, Ye Yang

Inorganic nanoparticles (NPs) are studied as drug carriers, radiosensitizers and imaging agents, and characterizing nanoparticle biodistribution is essential for evaluating their efficacy and safety. Tracking NPs at the single-cell level with current techn ...

Nature Publishing Group2017

Nanoparticles comprising a metal core surrounded by a monolayer for lymph node targeting

Francesco Stellacci, Ye Yang, Ahmet Bekdemir

Amphiphilic gold nanoparticles (amph-NPs), composed of gold cores surrounded by an amphiphilic mixed organic ligand shell, are capable of embedding within and traversing lipid membranes. Active agent is bound thereto for use in vaccine and other adjuvant t ...

2017

Influence of the glycocalyx and plasma membrane composition on amphiphilic gold nanoparticle association with erythrocytes

Francesco Stellacci, Paulo Henrique Jacob Silva, Ahmet Bekdemir, Randy Patrick Carney, Ye Yang

Erythrocytes are attractive as potential cell-based drug carriers because of their abundance and long life-span in vivo. Existing methods for loading drug cargos into erythrocytes include hypotonic treatments, electroporation, and covalent attachment onto ...

Royal Society of Chemistry2015

Enhancing Radiotherapy by Lipid Nanocapsule-Mediated Delivery of Amphiphilic Gold Nanoparticles to Intracellular Membranes

Francesco Stellacci, Randy Patrick Carney, Ye Yang

Amphiphilic gold nanoparticles (amph-NPs), composed of gold cores surrounded by an amphiphilic mixed organic ligand shell, are capable of embedding within and traversing lipid membranes. Here we describe a strategy using crosslink-stabilized lipid nanocaps ...

American Chemical Society2014

Effect of Particle Diameter and Surface Composition on the Spontaneous Fusion of Monolayer-Protected Gold Nanoparticles with Lipid Bilayers

Francesco Stellacci, Randy Patrick Carney, Ye Yang

Anionic, monolayer-protected gold nanoparticles (AuNPs) have been shown to nondisruptively penetrate cellular membranes. Here, we show that a critical first step in the penetration process is potentially the fusion of such AuNPs with lipid bilayers. Free e ...

American Chemical Society2013

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pH-Mediated molecular differentiation for fluorimetric quantification of chemotherapeutic drugs in human plasma

Francesco Stellacci, Stefan Guldin, Ye Yang

Royal Society of Chemistry2018

Structure-Property Relationships of Amphiphilic Nanoparticles That Penetrate or Fuse Lipid Membranes

Francesco Stellacci, Davide Demurtas, Paulo Henrique Jacob Silva, Randy Patrick Carney, Ye Yang, Ahmet Bekdemir, Zekiye Pelin Güven

2018

Influence of the glycocalyx and plasma membrane composition on amphiphilic gold nanoparticle association with erythrocytes

Francesco Stellacci, Paulo Henrique Jacob Silva, Ahmet Bekdemir, Randy Patrick Carney, Ye Yang

Royal Society of Chemistry2015

Nanoparticles comprising a metal core surrounded by a monolayer for lymph node targeting

Francesco Stellacci, Ye Yang, Ahmet Bekdemir

2017

High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry

Francesco Stellacci, Ahmet Bekdemir, Li Tang, Ye Yang

Nature Publishing Group2017

Enhancing Radiotherapy by Lipid Nanocapsule-Mediated Delivery of Amphiphilic Gold Nanoparticles to Intracellular Membranes

Francesco Stellacci, Randy Patrick Carney, Ye Yang

Amphiphilic gold nanoparticles (amph-NPs), composed of gold cores surrounded by an amphiphilic mixed organic ligand shell, are capable of embedding within and traversing lipid membranes. Here we describe a strategy using crosslink-stabilized lipid nanocaps ...

American Chemical Society2014

Effect of Particle Diameter and Surface Composition on the Spontaneous Fusion of Monolayer-Protected Gold Nanoparticles with Lipid Bilayers

Francesco Stellacci, Randy Patrick Carney, Ye Yang

American Chemical Society2013