Kai Johnsson, Luc Reymond, Georgios Hatzopoulos, Aleksandar Salim
Polo-like kinase (Plk4) is a serine/threonine-proteinkinase thatis essential for biogenesis of the centriole organelle and is enrichedat centrioles. Herein, we introduce Cen-TCO, a chemical probe basedon the Plk4 inhibitor centrinone, to image Plk4 and cen ...
AMER CHEMICAL SOC2023