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Peter Modregger

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Related publications (19)

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Alzheimer's disease (AD) is a looming threat on an ever-ageing population, with devastating effects on the human intellect. A particular characteristic lesion - the extracellular amyloid plaque - accumulates in the brain of AD patients during the course of ...

Institute of Physics2013

Iterative FBP For Improved Reconstruction Of X-Ray Differential Phase-Contrast Tomograms

Michaël Unser, Cédric René Jean Vonesch, Peter Modregger, Masih Nilchian, Marco Stampanoni

X-ray differential phase-contrast tomography is a recently-developed modality for the imaging of low-contrast biological samples. Its mathematical model is based on the first derivative of the Radon transform and the images, in practice, are reconstructed ...

IEEE2013

Off-the-shelf human decellularized tissue-engineered heart valves in a non-human primate model

Peter Modregger, Marco Stampanoni, Chad Brokopp

Heart valve tissue engineering based on decellularized xenogenic or allogenic starter matrices has shown promising first clinical results. However, the availability of healthy homologous donor valves is limited and xenogenic materials are associated with i ...

Elsevier2013

Imaging brain amyloid deposition using grating-based differential phase contrast tomography

Patrick Aebischer, Jean-Charles Bensadoun, Peter Modregger, Marco Stampanoni

One of the core pathological features of Alzheimer's disease (AD) is the accumulation of amyloid plaques in the brain. Current efforts of medical imaging research aim at visualizing amyloid plaques in living patients in order to evaluate the progression of ...

Elsevier2012

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Prenatal heart valve interventions aiming at the early and systematic correction of congenital cardiac malformations represent a promising treatment option in maternal-fetal care. However, definite fetal valve replacements require growing implants adaptive ...

2012

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We report on a setup for differential x-ray phase-contrast imaging and tomography, that measures the full 2D phase-gradient information. The setup uses a simple one-dimensional x-ray grating interferometer, in which the grating structures of the interferom ...

Optical Society of America2012

Engineering of living autologous human umbilical cord cell-based septal occluder membranes using composite PGA-P4HB matrices

Peter Modregger, Marco Stampanoni

Interventional closure of intracardiac wall defects using occluder devices has evolved as a highly attractive treatment option. However, incomplete and delayed healing reactions often result in a major risk of residual defects, thromboembolism, or device f ...

2011

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It is known that the sensitivity of X-ray phase-contrast grating interferometry with regard to electron density variations present in the sample is related to the minimum detectable refraction angle. In this article a numerical framework is developed that ...

Optical Society of America2011

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X-ray grating interferometry is a well established technique to perform differential phase contrast imaging on conventional x-ray tubes. So far, the application of this technique in commercial micro computed tomography scanners has remained a major challen ...

American Institute of Physics2011