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Karim Laurent Gariani

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Karim Laurent Gariani

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Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7

De novo NAD(+) synthesis enhances mitochondrial function and improves health

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis

The therapeutic role of NAD+ modulation in fatty liver disease

Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

NAD(+) repletion improves muscle function in muscular dystrophy and counters global PARylation

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease