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Marie Shamseddin

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Related publications (5)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation

Cathrin Brisken, Giovanna Ambrosini, Laura Battista, Philipp Bucher, Valentina Scabia, Fabio De Martino, Marie Shamseddin, Céline Berthe Constantin, Csaba Ferenc László

Hormonal contraception exposes women to synthetic progesterone receptor (PR) agonists, progestins, and transiently increases breast cancer risk. How progesterone and progestins affect the breast epithelium is poorly understood because we lack adequate mode ...

2021

Variably Scaled Kernels Improve Classification of Hormonally-Treated Patient-Derived Xenografts

Cathrin Brisken, Fabio De Martino, Marie Shamseddin, Francesco Marchetti

Little is known about the biological functions which are exerted by hormone receptors in physiological conditions. Here, we made use of the Mouse INtraDuctal (MIND) model, an innovative patient-derived xenograft (PDX) model, to characterize global gene exp ...

IEEE2020

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

Cathrin Brisken, Giovanna Ambrosini, Marian Caikovski, Dalya Ataca, Philipp Bucher, Renuga Devi Rajaram, Patrik Aouad, Marie Shamseddin, Céline Berthe Constantin, Csaba Ferenc László

Estrogens and progesterone control breast development and carcinogenesis via their cognate receptors expressed in a subset of luminal cells in the mammary epithelium. How they control the extracellular matrix, important to breast physiology and tumorigenes ...

Nature Research2020