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Andrea Ablasser

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Andrea Ablasser

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Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

TLR8-driven IL-12-dependent reciprocal and synergistic activation of NK cells and monocytes by immunostimulatory RNA

Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes

T cell-independent, TLR-induced IL-12p70 production in primary human monocytes