Person
Maria Soler Aznar
This person is no longer with EPFL
Related publications (10)
An integrated nanoplasmonic biosensor for monitoring cytokine secretion from single cells
Hatice Altug, George Coukos, Xiaokang Li, Filiz Yesilköy, Alexander Belushkin, Maria Soler Aznar
An innovative nanoplasmonic biosensor was presented for real-time label-free monitoring of cytokine secretion at single-cell resolution. This biosensor is integrated with a uniquely designed microfluidic device that provides a microchamber for cell incubat ...
IEEE2019Optofluidic nanoplasmonic biosensor for label-free live cell analysis in real time
Hatice Altug, Xiaokang Li, Filiz Yesilköy, Alexander Belushkin, Maria Soler Aznar
Cell signaling activities play a critical role in physiological and disease processes. The analysis of the tumor microenvironment or the immune system activation is nowadays providing valuable insights towards disease understanding and novel therapies deve ...
2018Towards a point-of-care nanoplasmonic biosensor for rapid and multiplexed detection of pathogenic infections
Hatice Altug, Xiaokang Li, Filiz Yesilköy, Alexander Belushkin, Maria Soler Aznar
The implementation of multiplexed point-of-care biosensors is a top priority to address the current epidemic problems originated by widespread pathogenic infections, like those caused by viruses or bacteria. A rapid and accurate detection, identification, ...
SPIE-INT SOC OPTICAL ENGINEERING2018Mining the Potential of Label-Free Biosensors for In Vitro Antipsychotic Drug Screening
Sandro Carrara, Hatice Altug, Tugba Kilic, Maria Soler Aznar
The pharmaceutical industry is facing enormous challenges due to high drug attribution rates. For the past decades, novel methods have been developed for safety and efficacy testing, as well as for improving early development stages. In vitro screening met ...
2018Label-Free Optofluidic Nanobiosensor Enables Real-Time Analysis of Single-Cell Cytokine Secretion
Hatice Altug, George Coukos, Xiaokang Li, Maria Soler Aznar
Single-cell analysis of cytokine secretion is essential to understand the heterogeneity of cellular functionalities and develop novel therapies for multiple diseases. Unraveling the dynamic secretion process at single-cell resolution reveals the real-time ...
2018Two-Dimensional Label-Free Affinity Analysis of Tumor-Specific CD8 T Cells with a Biomimetic Plasmonic Sensor
Hatice Altug, George Coukos, Xiaokang Li, Aurélian Michel John-Herpin, Maria Soler Aznar
The screening and analysis of T cells functional avidity for specific tumor-associated antigens is crucial for the development of personalized immunotherapies against cancer. The affinity and kinetics of a T cell receptor (TCR) binding to the peptide-major ...
AMER CHEMICAL SOC2018Plasmonic nanohole array biosensor for label-free and real-time analysis of live cell secretion
Hatice Altug, Xiaokang Li, Filiz Yesilköy, Alexander Belushkin, Maria Soler Aznar, Cenk Ibrahim Özdemir
Cell secretion dynamics plays a central role in physiological and disease processes. Due to its various temporal profiles, it is essential to implement a precise detection scheme for continuous monitoring of secretion in real time. The current fluorescent ...
Royal Society of Chemistry2017Multiplexed nanoplasmonic biosensor for one-step simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine
Hatice Altug, Andrea Cavallini, Alexander Belushkin, Maria Soler Aznar
Development of rapid and multiplexed diagnostic tools is a top priority to address the current epidemic problem of sexually transmitted diseases. Here we introduce a novel nanoplasmonic biosensor for simultaneous detection of the two most common bacterial ...
2017Recent advances in nanoplasmonic biosensors: applications and lab-on-a-chip integration
Motivated by the recent progress in the nanofabrication field and the increasing demand for cost--effective, portable, and easy-to-use point-of-care platforms, localized surface plasmon resonance (LSPR) biosensors have been subjected to a great scientific ...
Walter De Gruyter Gmbh2017Label-free nanoplasmonic sensing of tumor-associate autoantibodies for early diagnosis of colorectal cancer
Colorectal cancer is treatable and curable when detected at early stages. However there is a lack of less invasive and more specific screening and diagnosis methods which would facilitate its prompt identification. Blood circulating autoantibodies which ar ...
Elsevier Science Bv2016