Person
Torgil Elias Friman
This person is no longer with EPFL
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Related publications (6)
Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.
The role of OCT4 and SOX2 in regulating chromatin accessibility and cell fate across the cell cycle in embryonic stem cells
Precise spatiotemporal regulation of gene expression is essential for development and homeostasis of complex organisms. This is achieved in large part by sequence-specific transcription factors (TF) that bind to genomic regulatory elements to activate or r ...
EPFL2019Endogenous fluctuations of OCT 4 and SOX 2 bias pluripotent cell fate decisions
David Michael Suter, Cédric Deluz, Torgil Elias Friman, Andrea Brigitta Alber, Subashika Govindan, Daniel Strebinger
SOX2 and OCT4 are pioneer transcription factors playing a key role in embryonic stem (ES) cell self‐renewal and differentiation. How temporal fluctuations in their expression levels bias lineage commitment is unknown. Here, we generated knock‐in reporter f ...
2019Mitotic chromosome binding predicts transcription factor properties in interphase
David Michael Suter, Cédric Deluz, Torgil Elias Friman, Andrea Brigitta Alber, Mahé Cécile Raccaud
Mammalian transcription factors (TFs) differ broadly in their nuclear mobility and sequence-specific/non-specific DNA binding. How these properties affect their ability to occupy specific genomic sites and modify the epigenetic landscape is unclear. The as ...
2019