Person

Pavlo Khodakivskyi

This person is no longer with EPFL

Related publications (6)

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

A fatty-acid based probe for near-infrared fluorescence guided surgery of glioblastoma

Elena Goun, Pavlo Khodakivskyi

High-grade gliomas (HGG) are the most common and most aggressive primary tumors of the brain. Despite recent advances in neuro-oncology survival of these tumors remains around 12-15 months. The first-line of treatment is surgical resection. However, due to ...

Spie-Int Soc Optical Engineering2024

Bioluminescent compositions and uses thereof

Elena Goun, Pavlo Khodakivskyi, Hacer Karatas, Aleksey Yevtodiyenko

Compositions and methods for non-invasively monitoring the intracellular processing of a biomolecule are provided. The compositions have a novel thio-luciferin moiety which can be conjugated to the biomolecule directly or via a linker such as disulfide bon ...

2021

Optimized protocols for the synthesis of diazolyl alpha,alpha-difluoroacetates via deoxofluorination of the corresponding glyoxylates with Morph-DAST are described. The method allowed the preparation of the title fluoridated building blocks in 73-96 % yiel ...

ELSEVIER SCIENCE SA2020

Bioluminescent-based imaging and quantification of glucose uptake in vivo

Riccardo Sinisi, Elena Goun, Pavlo Khodakivskyi, Arkadiy Bazhin, Aleksey Yevtodiyenko, Tamara Maric, Georgy Mikhaylov

Glucose is a major source of energy for most living organisms, and its aberrant uptake is linked to many pathological conditions. However, our understanding of disease-associated glucose flux is limited owing to the lack of robust tools. To date, positron- ...

NATURE PUBLISHING GROUP2019

Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice

Pavlo Khodakivskyi

The kidney's inherent complexity has made identifying cell-specific pathways challenging, particularly when temporally associating them with the dynamic pathophysiology of acute kidney injury (AKI). Here, we combine renal cell-specific luciferase reporter ...

Springer2019

, ,

Introduction: Diagnosing-prosthetic joint infection (PJI) poses significant challenges, and current modalities are fraught with low sensitivity and/or potential morbidity. Photoacoustic imaging (PAI) is a novel ultrasound-based modality with potential for ...

Lippincott Williams & Wilkins2017