Diego Ghezzi

Biography

Prof. Diego Ghezzi holds the Medtronic Chair in Neuroengineering at the School of Engineering at the Ecole Polytechnique Fédérale de Lausanne. He received his M.Sc. in Biomedical Engineering (2004) and Ph.D. in Bioengineering (2008) from Politecnico di Milano. From 2008 to 2013, he completed his postdoctoral training at Istituto Italiano di Tecnologia in Genova at the Department of Neuroscience and Brain Technologies; where he was promoted to Researcher in 2013. In 2015, he was appointed as Tenure-Track Assistant Professor of Bioengineering at the EPFL Center for Neuroprosthetics and Institute of Bioengineering.

Official source

https://people.epfl.ch/diego.ghezzi

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Engineering Materials for Neurotechnology

Diego Ghezzi

Neurotechnology applies methods and devices to mitigate the burden of neurological and mental disorders. In particular, neural interfaces establish a long-term, seamless, symbiotic integration between implants and neural tissue. Materials play a pivotal role in neurotechnology. Advanced materials and materials engineering are crucial to achieving the desired function and outcome. Recently, neural interfaces extended their range of applications with the emergence of flexible, conformable, stretchable, injectable, and transient electronics. However, despite this enormous advancement in materials science and engineering, clinical devices still rely on old-fashioned but reliable materials and processes. The gap between research development and industry adoption has recently gained high interest. This article analyzes recent developments, discusses roadblocks, and provides a roadmap for materials engineering applied to neurotechnology.

WILEY-V C H VERLAG GMBH2023

Objective. Artificial vision has been and still is the subject of intense research. The ultimate goal is to help blind people in their daily life. Approaches to artificial vision, including visual prostheses and optogenetics, have strongly focused on restoring high visual acuity for object recognition and reading. Consequently, clinical trials were primarily focused on these parameters. Approach. Alternatively, enlarging the visual field (VF) size could significantly improve artificial vision. Main results. I propose that approaches towards artificial vision address the challenge of creating this rudimental form of sight within a large VF. Significance. Enlarging the VF size will enable users to improve their mobility and perform visually-driven search tasks. Eventually, it could make artificial vision more efficient, comfortable and acceptable from the user's point of view.

IOP Publishing Ltd2023

Vision is an extraordinary sense through which we can appreciate the beauty of the world we live in, gain invaluable knowledge and communicate with others using visual expression and arts. On the contrary, blindness is a threatening medical condition disrupting the life of affected people and their families. Therefore, restoring sight is one of the open challenges of our society. Today, the synergistic convergence of science and technology holds the potential to provide blind patients with artificial vision using visual prostheses: a type of implantable medical device able to reactivate visual neurons using electrical stimulation. Although clinical trials showed that vision restoration is still far away, significant technological advances make visual prostheses a valuable solution for blind patients. This review is not only a description of the state-of-the-art. Instead, it provides the reader with an update on recent developments, a critical discussion of the open challenges, and an overview of promising future directions.

IOP Publishing Ltd2022