Publications by Mandresy Ivan Ny Hanitra

All-Solid-State Ion-Selective Electrodes: A Tutorial for Correct Practice

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Irene Taurino, Francesca Criscuolo

The research on ion-measuring devices has seen a rapid expansion in the last years as a consequence of the growing interest in wearable sensors for biofluids analysis and in portable devices for remote or in-line water and food quality monitoring. As a res ...

2021

Hardware and Software Interfaces Design for Multi-Panel Electrochemical Sensors

Mandresy Ivan Ny Hanitra

The exponential growth of wearable healthcare devices market is fostered by the internetof- things (IoT) era. Connected smart biosensors enable a decentralized healthcare that does not constrain the user to be in a medical facility to get a real-time insig ...

EPFL2021

Smart Portable Pen for Continuous Monitoring of Anaesthetics in Human Serum With Machine Learning

Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi, Simone Aiassa

Continuous monitoring of anaesthetics infusion is demanded by anaesthesiologists to help in defining personalized dose, hence reducing risks and side effects. We propose the first piece of technology tailored explicitly to close the loop between anaesthesi ...

2021

Multi-ion-sensing emulator and multivariate calibration optimization by machine learning models

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Francesca Criscuolo

One paramount challenge in multi-ion-sensing arises from ion interference that degrades the accuracy of sensor calibration. Machine learning models are here proposed to optimize such multivariate calibration. However, the acquisition of big experimental da ...

2021

Real-Time Multi-Ion-Monitoring Front-End With Interference Compensation by Multi-Output Support Vector Regressor

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Francesca Criscuolo

Ion-sensors play a major role in physiology and healthcare monitoring since they are capable of continuously collecting biological data from body fluids. Nevertheless, ion interference from background electrolytes present in the sample is a paramount chall ...

2021

Multi-Channel Front-End for Electrochemical Sensing of Metabolites, Drugs, and Electrolytes

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Francesca Criscuolo, Nadezda Pankratova

A multi-channel front-end for electrochemical sensing is presented. It consists of a multiplexed four-channel readout interface supporting amperometric, voltammetric, and potentiometric measurements. The electronic interface is co-designed according to the ...

2020

Emulator Design and Generation of Synthetic Dataset in Multi-Ion Sensing

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi

Multi-ion potentiometric sensing becomes challenging for mixed-ion samples in which interfering electrolytes significantly alter the response of each single sensor. Therefore, an emulator based on the phase-boundary potential model is proposed to simulate ...

IEEE2020

Wearable multifunctional sweat-sensing system for efficient healthcare monitoring

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Irene Taurino, Francesca Criscuolo, Nicolò Oliva, Simone Aiassa

Despite the huge expansion in recent years of sweat sensing and wearable technologies, several challenges are still open, including poor sample collection, separate sampling and analysis, low multi-sensing capabilities and materials toxicity. In this work, ...

2020

Continuous monitoring of propofol in human serum with fouling compensation by support vector classifier

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi, Francesca Criscuolo, Simone Aiassa, Francesco Grassi, Tiberiu Totu, Gabriele Sandri

We present a new method for electrochemical sensing, which compensates the fouling effect of propofol through machine learning (ML) model. Direct and continuous monitoring of propofol is crucial in the development of automatic systems for control of drug i ...

Elsevier2020

Multi-Target Electrolyte Sensing Front-End for Wearable Physical Monitoring

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Francesca Criscuolo

Wearable physiology is an expanding field, especially for sports applications that steadily require an accurate monitoring of the physical status of athletes. This work presents the co-design and the realization of an hardware front-end that enables multi- ...

IEEE2019