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Ganesh Kumar Mothukuri

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Ganesh Kumar Mothukuri

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Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation

Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides

Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

In Vitro-Evolved Peptides Bind Monomeric Actin and Mimic Actin-Binding Protein Thymosin-β4

Macrocycle synthesis strategy based on step-wise “adding and reacting” three components enables screening of large combinatorial libraries

Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation

In Vitro-Evolved Peptides Bind Monomeric Actin and Mimic Actin-Binding Protein Thymosin-β4

Macrocycle synthesis strategy based on step-wise “adding and reacting” three components enables screening of large combinatorial libraries

Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides

Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale