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Maartje Martina Cornelia Bastings

Related publications (27)

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Engineering a stable future for DNA-origami as a biomaterial

Maartje Martina Cornelia Bastings, Eva Eugene Kurisinkal, Hale Bila

DNA as a biomaterial has evoked great interest as a potential platform for therapeutics and diagnostics and as hydrogel scaffolds due to the relative ease of programming its robust and uniform shape, site-specific functionality and controlled responsive be ...

ROYAL SOC CHEMISTRY2019

The most basic function of synthetic microenvironments for tissue engineering is to act as a physical substrate for cell attachment, migration, and proliferation, similar to the natural cell environment. Functionalization of supramolecular materials with g ...

WILEY-V C H VERLAG GMBH2019

Nucleic acids presenting polymer nanomaterials as vaccine adjuvants

Maartje Martina Cornelia Bastings, Kaltrina Paloja, Alice Comberlato

Most vaccines developed today include only the antigens that best stimulate the immune system rather than the entire virus or microbe, which makes vaccine production and use safer and easier, though they lack potency to induce acceptable immunity and long- ...

ROYAL SOC CHEMISTRY2019

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Understanding hierarchical self-assembly of biological structures requires real time measurement of the self-assembly process over a broad range of length- and timescales. The success of high-speed atomic force microscopy (HS-AFM) in imaging small scale mo ...

2019

Supramolecular Polymers in Aqueous Media

Maartje Martina Cornelia Bastings

This review discusses one-dimensional supramolecular polymers that form in aqueous media. First, naturally occurring supramolecular polymers are described, in particular, amyloid fibrils, actin filaments, and microtubules. Their structural, thermodynamic, ...

American Chemical Society2016

Adjuvant-Loaded Subcellular Vesicles Derived From Disrupted Cancer Cells for Cancer Vaccination

Maartje Martina Cornelia Bastings

Immunogenic subcellular vesicular particles that can be used to stimulate antigen-specific immune responses in vitro and in vivo are generated from whole cancer cells. The particles retain a broad antigen repertoire similar to that of the parent cells, and ...

Wiley-Blackwell2016

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Maartje Martina Cornelia Bastings

Regeneration of lost myocardium is an important goal for future therapies because of the increasing occurrence of chronic ischemic heart failure and the limited access to donor hearts. An example of a treatment to recover the function of the heart consists ...

Journal of Visualized Experiments2015

Sustained Delivery of Insulin-Like Growth Factor-1/Hepatocyte Growth Factor Stimulates Endogenous Cardiac Repair in the Chronic Infarcted Pig Heart

Maartje Martina Cornelia Bastings

Activation of endogenous cardiac stem/progenitor cells (eCSCs) can improve cardiac repair after acute myocardial infarction. We studied whether the in situ activation of eCSCs by insulin-like growth factor 1 (IGF-1) and hepatocyte growth factor (HGF) could ...

2014

Hydrogels and, in particular, supramolecular hydrogels show promising properties for application in regenerative medicine because of their ability to adapt to the natural environment these materials are brought into. However, only few studies focus on the ...

MDPI2014

The aim of this study was to test the sustained release of insulin-like growth factor-1 (IGF-1) and hepatocyte growth factor (HGF) using an injectable supramolecular hydrogel based on ureido-pyrimidinone (UPy) moieties in order to recruit and activate endo ...

2013