Publications by Maximilian Jonas Wessel

Brain Oscillatory Modes as a Proxy of Stroke Recovery

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Silvestro Micera, Friedhelm Christoph Hummel, Takuya Morishita, Elena Beanato, Sylvain Jean-François Harquel, Lisa Aïcha Mireille Julie Fleury, Nathalie Heidi Meyer, Maximilian Jonas Wessel

Background Stroke is the leading cause of long-term disability, making the search for successful rehabilitation treatment one of the most important public health issues. A better understanding of the neural mechanisms underlying impairment and recovery is ...

SAGE Publications2025

Safety, tolerability and blinding efficiency of non-invasive deep transcranial temporal interference stimulation: first experience from more than 250 sessions

Friedhelm Christoph Hummel, Pierre Theopistos Vassiliadis, Elena Beanato, Fabienne Windel, Emma Marie D Stiennon, Maximilian Jonas Wessel

Objective. Selective neuromodulation of deep brain regions has for a long time only been possible through invasive approaches, because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques. Approach. An appr ...

Iop Publishing Ltd2024

Noninvasive modulation of the hippocampal-entorhinal complex during spatial navigation in humans

Olaf Blanke, Friedhelm Christoph Hummel, Pierre Theopistos Vassiliadis, Elena Beanato, Esra Neufeld, Emanuela De Falco, Fabienne Windel, Maximilian Jonas Wessel, Traian Popa, Baptiste Gauthier

Because of the depth of the hippocampal-entorhinal complex (HC-EC) in the brain, understanding of its role in spatial navigation via neuromodulation was limited in humans. Here, we aimed to better elucidate this relationship in healthy volunteers, using tr ...

American Association for the Advancement of Science (AAAS)2024

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

Friedhelm Christoph Hummel, Takuya Morishita, Pierre Theopistos Vassiliadis, Elena Beanato, Esra Neufeld, Fabienne Windel, Maximilian Jonas Wessel, Traian Popa, Julie Duqué

Reinforcement feedback can improve motor learning, but the underlying brain mechanisms remain underexplored. In particular, the causal contribution of specific patterns of oscillatory activity within the human striatum is unknown. To address this question, ...

Nature Portfolio2024

Differential Impact of Brain Network Efficiency on Poststroke Motor and Attentional Deficits

Dimitri Nestor Alice Van De Ville, Friedhelm Christoph Hummel, Gabriel Girard, Takuya Morishita, Elena Beanato, Lisa Aïcha Mireille Julie Fleury, Nathalie Heidi Meyer, Maximilian Jonas Wessel, Philip Egger, Philipp Johannes Koch

Background:Most studies on stroke have been designed to examine one deficit in isolation; yet, survivors often have multiple deficits in different domains. While the mechanisms underlying multiple-domain deficits remain poorly understood, network-theoretic ...

2023

Mini-review: Transcranial Alternating Current Stimulation and the Cerebellum

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Laurijn Rianne Draaisma

Oscillatory activity in the cerebellum and linked networks is an important aspect of neuronal processing and functional implementation of behavior. So far, it was challenging to quantify and study cerebellar oscillatory signatures in human neuroscience due ...

2023

Multi-focal Stimulation of the Cortico-cerebellar Loop During the Acquisition of a Novel Hand Motor Skill in Chronic Stroke Survivors

Friedhelm Christoph Hummel, Takuya Morishita, Pablo Maceira Elvira, Manon Chloé Durand-Ruel, Maximilian Jonas Wessel, Philipp Johannes Koch, Laurijn Rianne Draaisma

Impairment of hand motor function is a frequent consequence after a stroke and strongly determines the ability to regain a self-determined life. An influential research strategy for improving motor deficits is the combined application of behavioral trainin ...

2023

Novel personalized treatment strategy for patients with chronic stroke with severe upper-extremity impairment: The first patient of the AVANCER trial

Friedhelm Christoph Hummel, Takuya Morishita, Andrea Crema, Elena Beanato, Sylvain Jean-François Harquel, Maximilian Jonas Wessel, Claudia Bigoni, Giorgia Giulia Evangelista, Sarah Bernardina Zandvliet

Background: Around 25% of patients who have had a stroke suffer from severe upper-limb impairment and lack effective rehabilitation strategies. The AVANCER proof-of-concept clinical trial (NCT04448483) tackles this issue through an intensive and personaliz ...

CELL PRESS2023

Noninvasive theta-burst stimulation of the human striatum enhances striatal activity and motor skill learning

Friedhelm Christoph Hummel, Takuya Morishita, Pablo Maceira Elvira, Pierre Theopistos Vassiliadis, Elena Beanato, Fabienne Windel, Esra Neufeld, Maximilian Jonas Wessel, Chang-Hyun Park, Traian Popa

The stimulation of deep brain structures has thus far only been possible with invasive methods. Transcranial electrical temporal interference stimulation (tTIS) is a novel, noninvasive technology that might overcome this limitation. The initial proof-of-co ...

Nature Portfolio2023

Dissecting motor skill acquisition: Spatial coordinates take precedence

Friedhelm Christoph Hummel, Takuya Morishita, Pablo Maceira Elvira, Traian Popa, Anne-Christine Schmid, Maximilian Jonas Wessel

Practicing a previously unknown motor sequence often leads to the consolidation of motor chunks, which enable its accurate execution at increasing speeds. Recent imaging studies suggest the function of these structures to be more related to the encoding, s ...

AMER ASSOC ADVANCEMENT SCIENCE2022