Person

Abdul Jabbar

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Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain

Johan Auwerx, Martinus Gijs, Matteo Cornaglia, Laurent Mouchiroud, Abdul Jabbar

As a result of limited classes of anthelmintics and an over-reliance on chemical control, there is a great need to discover new compounds to combat drug resistance in parasitic nematodes. Here, we show that deguelin, a plant-derived rotenoid, selectively a ...
Federation Amer Soc Exp Biol2017

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