Person
Maria Pasquini
This person is no longer with EPFL
Related publications (7)
Fast-Spiking Interneurons of the Premotor Cortex Contribute to Initiation and Execution of Spontaneous Actions
Silvestro Micera, Maria Pasquini
Planning and execution of voluntary movement depend on the contribution of distinct classes of neurons in primary motor and premotor areas. However, timing and pattern of activation of GABAergic cells during specific motor behaviors remain only partly unde ...
SOC NEUROSCIENCE2023Combining robotics with enhanced serotonin-driven cortical plasticity improves post-stroke motor recovery
Silvestro Micera, Stefano Lai, Maria Pasquini, Sara Conti, Marco Mainardi
Despite recent progresses in robotic rehabilitation technologies, their efficacy for post-stroke motor recovery is still limited. Such limitations might stem from the insufficient enhancement of plasticity mechanisms, crucial for functional recovery. Here, ...
PERGAMON-ELSEVIER SCIENCE LTD2021Combining Optogenetic Stimulation and Motor Training Improves Functional Recovery and Perilesional Cortical Activity
Silvestro Micera, Maria Pasquini, Francesco Saverio Pavone
Background. An ischemic stroke is followed by the remapping of motor representation and extensive changes in cortical excitability involving both hemispheres. Although stimulation of the ipsilesional motor cortex, especially when paired with motor training ...
SAGE PUBLICATIONS INC2021Experimental and Computational Study on Motor Control and Recovery After Stroke: Toward a Constructive Loop Between Experimental and Virtual Embodied Neuroscience
Auke Ijspeert, Silvestro Micera, Shravan Tata Ramalingasetty, Marc-Oliver Gewaltig, Emanuele Formento, Maria Pasquini, Egidio Falotico, Lorenzo Vannucci, Axel von Arnim, Emmanouil Angelidis, Alain Destexhe
Being able to replicate real experiments with computational simulations is a unique opportunity to refine and validate models with experimental data and redesign the experiments based on simulations. However, since it is technically demanding to model all ...
FRONTIERS MEDIA SA2020Combined rehabilitation promotes recovery of motor functionality in a mouse model of stroke
Silvestro Micera, Maria Pasquini
Neuro-rehabilitative research is developing novel strategies to enhance the effectiveness of therapies after stroke by using a combination of physical and plasticizing treatments 1-3. Previous studies have shown that repeated optogenetics stimulation of ne ...
SPIE-INT SOC OPTICAL ENGINEERING2019Wide-field imaging of cortical neuronal activity with red-shifted functional indicators during motor task execution
Silvestro Micera, Maria Pasquini, Francesco Saverio Pavone
Genetically encoded calcium indicators (GECIs) can be used to monitor the intracellular concentration of free calcium in populations of neurons. GECIs with long emission wavelengths are particularly attractive for deep tissue microscopy in vivo, and have t ...
IOP PUBLISHING LTD2019A Robotic System for Adaptive Training and Function Assessment of Forelimb Retraction in Mice
Silvestro Micera, Stefano Lai, Maria Pasquini, Sara Conti
Rodent models are decisive for translational research in healthy and pathological conditions of motor function thanks to specific similarities with humans. Here, we present an upgraded version of the M-Platform, a robotic device previously designed to trai ...
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2018