Person
Yi Zhao
This person is no longer with EPFL
Related publications (6)
AIDRES: A database for the decarbonisation of the heavy industry in Europe
François Maréchal, Luc Girardin, Daniel Alexander Florez Orrego, Ivan Daniel Kantor, Shivom Sharma, Meire Ellen Gorete Ribeiro Domingos, Rafael Amorim Leandro De Castro Amoedo, Julia Granacher, Yi Zhao
The AIDRES database aims to support the long-term objective of a fully integrated industrial strategy in the EU 27, providing a service to the European Commission and a catalogue for industries to understand the effectiveness, efficiency and cost of potent ...
Universidad de Las Palmas de Gran Canaria2023Z-REX uncovers a bifurcation in function of Keap1 paralogs
Yimon Aye, Jesse Poganik, Xuyu Liu, Yi Zhao, Kuan-Ting Huang
Studying electrophile signaling is marred by difficulties in parsing changes in pathway flux attributable to on-target, vis-& agrave;-vis off-target, modifications. By combining bolus dosing, knockdown, and Z- REX & mdash;a tool investigating on- target/on ...
eLIFE SCIENCES PUBL LTD2022Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera
Yimon Aye, Sruthi Raja, Jesse Poganik, Yi Zhao, Kuan-Ting Huang
The mechanism-of-action of many electrohilic drugs remains poorly understood. Here, the authors use a redox-targeting approach to elucidate the basis for the innate immune cell toxicity of dimethyl fumarate, showing that it modifies Keap1 to trigger mitoch ...
NATURE PORTFOLIO2021Neighborhood watch: tools for defining locale-dependent subproteomes and their contextual signaling activities
Transient associations between numerous organelles-e.g., the endoplasmic reticulum and the mitochondria-forge highly-coordinated, particular environments essential for cross-compartment information flow. Our perspective summarizes chemical-biology tools th ...
ROYAL SOC CHEMISTRY2020The mRNA-Binding Protein HuR Is a Kinetically-Privileged Electrophile Sensor
Yimon Aye, Jesse Poganik, Yi Zhao, Alexandra Krina Van Hall-Beauvais
The key mRNA-binding proteins HuR and AUF1 are reported stress sensors in mammals. Intrigued by recent reports of sensitivity of these proteins to the electrophilic lipid prostaglandin A2 and other redox signals, we here examined their sensing abilities to ...
2020