Person
Eva Ramos Fernandez
This person is no longer with EPFL
Related publications (5)
Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function
Maria del Carmen Sandi Perez, Bernard Schneider, Jocelin Grosse, Olivia Zanoletti, Simone Astori, Elias Georges Gebara, Marie-Isabelle Guillot de Suduiraut, Alessandro Chioino, Sriparna Ghosal, Eva Ramos Fernandez
The nucleus accumbens (NAc) is a brain hub regulating motivated behaviors, including social competitiveness. Mitochondrial function in the NAc links anxiety with social competitiveness, and the mitochondrial fusion protein mitofusin 2 (Mfn2) in NAc neurons ...
2023Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort
Maria del Carmen Sandi Perez, Lijing Xin, Olivia Zanoletti, Simone Astori, João Pedro de Matos Rodrigues, Fiona Hollis, Pascal Steiner, Ioannis Zalachoras, Alina Veronika Irene Strasser, Eva Ramos Fernandez
Emerging evidence is implicating mitochondrial function and metabolism in the nucleus accumbens in motivated performance. However, the brain is vulnerable to excessive oxidative insults resulting from neurometabolic processes, and whether antioxidant level ...
2022Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2 alpha HRI kinase
Wnt signaling plays a key role in neurodevelopment and neuronal maturation. Specifically, Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and, through calcium signaling, generates nitric oxide (NO). Trying to unveil the ...
NATURE RESEARCH2021Astrocytic release of ATP through type 2 inositol 1,4,5‐trisphosphate receptor calcium signaling and social dominance behavior in mice
Maria del Carmen Sandi Perez, Jocelin Grosse, Marie-Isabelle Guillot de Suduiraut, Fiona Hollis, Eva Ramos Fernandez
Brain mitochondrial function is critical for numerous neuronal processes. We recently identified a link between brain energy and social dominance, where higher levels of mitochondrial function resulted in increased social competitive ability. The underlyin ...
2020Therapeutic potential of glutathione-enhancers in stress-related psychopathologies
Maria del Carmen Sandi Perez, Sarah Catherine Sonnay, Fiona Hollis, Pascal Steiner, Ioannis Zalachoras, Eva Ramos Fernandez, Laia Morato Fornaguera
The mammalian brain has high energy demands, which may become higher in response to environmental challenges such as psychogenic stress exposure. Therefore, efficient neutralization of reactive oxygen species that are produced as a by-product of ATP synthe ...
2020