Optofluidics of plants

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Microfluidic engineering of artificial stem cell niches

Stem cells play a key role in a wide range of biological processes, in large part due to their ability to self-renew or differentiate into specialized cell types in response to various biological cues. In vivo, stem cells reside in a complex microenvironme ...

EPFL2015

A microfluidic flow-cell for the study of the ultrafast dynamics of biological systems

Majed Chergui, Adrien Alexis Paul Chauvet

The study of biochemical dynamics by ultrafast spectroscopic methods is often restricted by the limited amount of liquid sample available, while the high repetition rate of light sources can induce photodamage. In order to overcome these limitations, we de ...

American Institute of Physics2014

Lensfree optofluidic plasmonic sensor for real-time and label-free monitoring of molecular binding events over a wide field-of-view

Hatice Altug, Arif Engin Cetin

We demonstrate a high-throughput biosensing device that utilizes microfluidics based plasmonic microarrays incorporated with dual-color on-chip imaging toward real-time and label-free monitoring of biomolecular interactions over a wide field-of-view of > 2 ...

Nature Publishing Group2014

Crossed fiber optic Bessel beams for curvilinear optofluidic transport of dielectric particles

René Salathé, Fabrice Merenda, Kyunghwan Oh

Due to its unique non-diffracting and self-reconstructing nature, Bessel beams have been successfully adopted to trap multiple particles along the beam's axial direction. However, prior bulk-optic based Bessel beams have a fundamental form-factor limitatio ...

Optical Soc Amer2013

Angular Resolved low loss EELS for Materials Characterization

Simon Schneider

Electron Energy Loss Spectrometry (EELS) in Transmission Electron Microscopy (TEM) is a powerful tool for the investigation of the electronic structure of materials. In the low loss regime, one can access the optical properties which are governed by the di ...

EPFL2013

Application of Adaptive Optics to Focusing and Imaging

Daniel Iwaniuk

Adaptive optics is used to abate aberrations with a wavefront correction. It is widely used in astronomy and is starting to expand into applications of laser focusing and imaging with high numerical apertures, e.g. microscopy. The physical background of fo ...

EPFL2012

Optical Trapping in Microfluidic Channels for Functional and Chemical Analysis of Single Cells

Michael Werner

The physiological properties of cells are typically investigated in ensembles yielding averaged data that mask heterogeneities present in any cell population. Single-cell analysis techniques based on microfluidic "lab on a chip" (LOC) devices have recently ...

EPFL2011

Microfluidic array cytometer based on refractive optical tweezers for parallel trapping, imaging and sorting of individual cells

René Salathé, Horst Vogel, Fabrice Merenda, Joachim Piguet, Michael Werner

Analysis of genetic and functional variability in populations of living cells requires experimental techniques capable of monitoring cellular processes such as cell signaling of many single cells in parallel while offering the possibility to sort interesti ...

Royal Society of Chemistry2011

Controlling and utilizing optical forces at the nanoscale with plasmonic antennas

Olivier Martin, Andrea Lovera

Plasmonic dipole antennas are powerful optical devices for many applications since they combine a high field enhancement with outstanding tunability of their resonance frequency. The field enhancement, which is mainly localized inside the nanogap between b ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2011

Integration of plasmonic trapping in a microfluidic environment

Olivier Martin, Sebastian Maerkl, Lina Huang

Near field generated by plasmonic structures has recently been proposed to trap small objects. We report the first integration of plasmonic trapping with microfluidics for lab-on-a-chip applications. A three-layer plasmo-microfluidic chip is used to demons ...

Optical Society of America2009

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