A Novel Strategy for the Design of 8-Hydroxyquinolinate- Based Lanthanide Bioprobes That Emit in the Near Infrared Range
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Metal ions are constituents of many metalloproteins, in which they have either catalytic (metalloenzymes) or structural functions. In this work, the characteristics of various metals were studied (Cu, Zn, Mg, Mn, Fe, Co, Ni, Cd and Ca in proteins with know ...
The potentially hexadentate ligand L, which contains two terminal coumarin fluorophores, forms dinuclear double-stranded helicates with dicationic metal ions, giving species of the generic form M2L2. In solution the free ligand was fluorescent with e ...
Microwave heating was employed to promote arene displacement in reactions of [{(p-cymene)RuCl2}(2)] or [{(1,3,5-C-6,H(3)iPr(3))RuCl2}(2)] with neutral chelate ligands L-L' [L-L': 1,1'-bis(diphenylphosphanyl)methane, 1,1'- bis(diphenylphosphanyl)ferrocene, ...
Deviations from statistical binding, that is cooperativity, in self-assembled polynuclear complexes partly result from intermetallic interactions Delta E-M,E-M, whose magnitudes in solution depend on a balance between electrostatic repulsion and solvation ...
Homonuclear helicates with rare-earth-metal(III) ions or heteronuclear derivatives with rare-earth-metal and aluminium or zinc centres are obtained in alkali-metal-templated selfassembly processes from isobutenylidene- bridged homoditopic bis(2-carb-Gamido ...
This Ph.D. work deals with the development of lanthanide-based bioprobes for biomedical analyses and imaging. For this purpose, two different approaches have been followed, one focusing on visible-emitting complexes, while the second addresses the sensitiz ...
The knowledge and understanding of the mechanism as well as the rate constant of the solvent exchange reactions are fundamental, since these reactions represent an important step in complex formation reactions on metal ions. Solvent exchange reactions in a ...
A series of lanthanide adducts with different amounts of 1,10-phenanthroline, chloride ions, and water molecules in the inner and outer coordination spheres are investigated with the aim of relating the chemical bonding pattern in the crystals to the lumin ...
A new class of benzimidazole-substituted 8-hydroxyquinoline ligands has been prepared that contain a monoanionic tridentate N,N,O-coordinating unit. These ligands form charge-neutral lanthanide complexes of the type [Ln(LR) 3] · nH2O or [Ln2(L2)3] · nH2O ( ...
Since contrasts agents are used in magnetic resonance imaging (MRI), numerous efforts have been done to increase their relaxivity (parameter allowing to quantify contrast agent efficiency). Few years ago, the Merbach group developed the chelating agent DTT ...