Human fetal bone cells associated with ceramic reinforced PLA scaffolds for tissue engineering
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Bone is a natural cellular composite, with a gradient structure going from a loose interconnected core to an outer dense wall, thus minimising bone weight while maintaining a high mechanical performance. Bone can be repaired using either auto- or allo- gra ...
We envision the use of human fetal bone cells for engineered regeneration of adult skeletal tissue. A description of their cellular function is then necessary. To our knowledge, there is no description of human primary fetal bone cells treated with differe ...
Total Hip Replacement (THR) is today a routine procedure executed more than 800'000 times per year worldwide. THR gives generally satisfactory results, although the quality of outcome is inversely proportional to the age of the patient. In parallel, there ...
NOVELTY - The bone substitute is made in one piece from cement phosphocalcium materials consolidated chemically at low temperature and in presence of water. USE - In medicine, as artificial bone graft. ADVANTAGE - Macroporous structure promotes resorption ...
Synthetic hydrogels have been molecularly engineered to mimic the invasive characteristics of native provisional extracellular matrixes: a combination of integrin-binding sites and substrates for matrix metalloproteinases (MMP) was required to render the n ...
We have engineered synthetic poly(ethylene glycol) (PEG)-based hydrogels as cell-ingrowth matrices for in situ bone regeneration. These networks contain a combination of pendant oligopeptide ligands for cell adhesion (RGDSP) and substrates for matrix metal ...
