The Genetics Company, Inc. - A newly founded Swiss Biotech Company

Markus Jenni, Michel Aguet
2000
Journal paper

Morphogenetic pathways govern the processes that underlie embryonic development as well as self-renewal and homeostasis in adult tissues. The Genetics Company (TGC) exploits the untapped potential of morphogenetic pathways to develop new therapeutic approaches to human diseases with an initial focus on cancer and type-2 diabetes. TGC has established Morphogenetics(TM) as a proprietary strategy: To identify and validate novel modulators of tissue and organ development for new therapeutic applications, ranging from the morphogenetic remodeling of tumors to in vitro tissue engineering and organ regeneration To identify new drug targets through in vivo saturation mutagenesis in Drosophila To identify small compounds by means of an innovative in vivo screening technology in Drosophila (InvoScreen(TM)).

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Markus Jenni, Michel Aguet
2000
Journal paper

Abstract

Official source

https://infoscience.epfl.ch/record/114727?ln=en

About this result

Related concepts (3)

Genetics

Genetics is the study of genes, genetic variation, and heredity in organisms. It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance".

Morphogenesis

Morphogenesis (from the Greek morphê shape and genesis creation, literally "the generation of form") is the biological process that causes a cell, tissue or organism to develop its shape. It is one of three fundamental aspects of developmental biology along with the control of tissue growth and patterning of cellular differentiation. The process controls the organized spatial distribution of cells during the embryonic development of an organism.

Disease

A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms. A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies, and autoimmune disorders.