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Long distance control of MHC class II expression by multiple distal enhancers regulated by regulatory factor X complex and CIITA
Related concepts (33)
Overlapping gene
An overlapping gene (or OLG) is a gene whose expressible nucleotide sequence partially overlaps with the expressible nucleotide sequence of another gene. In this way, a nucleotide sequence may make a contribution to the function of one or more gene products. Overlapping genes are present and a fundamental feature of both cellular and viral genomes. The current definition of an overlapping gene varies significantly between eukaryotes, prokaryotes, and viruses.
Gene knock-in
In molecular cloning and biology, a gene knock-in (abbreviation: KI) refers to a genetic engineering method that involves the one-for-one substitution of DNA sequence information in a genetic locus or the insertion of sequence information not found within the locus. Typically, this is done in mice since the technology for this process is more refined and there is a high degree of shared sequence complexity between mice and humans.
Length of a module
In algebra, the length of a module is a generalization of the dimension of a vector space which measures its size. page 153 It is defined to be the length of the longest chain of submodules. The modules of finite length are finitely generated modules, but as opposite to vector spaces, many finitely generated modules have an infinite length. Finitely generated modules of finite length are also called Artinian modules and are at the basis of the theory of Artinian rings. For vector spaces, the length equals the dimension.