Spatiotemporal dynamics of sensory responses in layer 2/3 of rat barrel cortex measured in vivo by voltage-sensitive dye imaging combined with whole-cell voltage recordings and neuron reconstructions
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Voltage-sensitive dye imaging resolves the spatiotemporal dynamics of supragranular subthreshold cortical activity with millisecond temporal resolution and subcolumnar spatial resolution. We used a flexible fiber optic image bundle to visualize voltage-sen ...
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Tactile information is actively acquired and processed in the brain through concerted interactions between movement and sensation. Somatosensory input is often the result of self-generated movement during the active touch of objects, and conversely, sensor ...
Local microcircuits within neocortical columns form key determinants of sensory processing. Here, we investigate the excitatory synaptic neuronal network of an anatomically defined cortical column, the C2 barrel column of mouse primary somatosensory cortex ...
Silicon biosensor microprobes for the in vivo detection of neurotransmitters are equipped with removable clips for an on-chip functionalisation technique that allows a simple and comfortable but very local and reproducible deposition of sensitive layers on ...
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Rodents are nocturnal animals gathering information about their surroundings by using highly sensitive detectors laid out on their snout. Like humans use their fingertips to apprehend textures, rodents use their whiskers to build a spatial representation o ...