beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
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The interest in new materials and their application in the neuroscience are growing incredibly fast. Current research interests are increasingly focusing on new artificial materials and their direct effects on the central nervous systems so that it would b ...
Polycystic diseases and left-right (LR) axis malformations are frequently linked to cilia defects. Renal cysts also arise in mice and frogs lacking Bicaudal C (BicC), a conserved RNA-binding protein containing K-homology (KH) domains and a sterile alpha mo ...
In the brainstem auditory circuit of mammals and birds, excitatory synapses with extraordinarily large size have evolved, which ensure fast membrane potential signaling mediated by large, multiquantal excitatory postsynaptic currents (EPSCs). The so-called ...
Here we describe the generation of the Nes-Cre1 transgenic mouse line in which Cre recombinase expression is controlled by the rat nestin promoter and intron 2 enhancer. This line has previously been used for conditional loss-of-function studies of various ...
The electric power system has often been compared to a circulatory system, and telecommunication and informational complexes likened to nervous systems. Such characterisations are rigorous only for those aspects that bring the utility system closer to a li ...
Monaco V, Ghionzoli A, Micera S. Age-related modifications of muscle synergies and spinal cord activity during locomotion. J Neurophysiol 104: 2092-2102, 2010. First published August 4, 2010; doi:10.1152/jn.00525.2009. Recent findings have shown that neura ...
To exert its activity, anthrax toxin must be endocytosed and its enzymatic toxic subunits delivered to the cytoplasm. It has been proposed that, in addition to the anthrax toxin receptors (ATRs), lipoprotein-receptor-related protein 6 (LRP6), known for its ...
BACKGROUND & AIMS: The mechanisms for tissue regeneration and renewal after acute pancreatitis are not well understood but may involve activation of Notch signaling. To study the effect of Notch signaling ablation during acute experimental pancreatitis, we ...
The ability of tracking peripheral nerves in foot could be of great benefit for a number of investigations, which include traumas, diabetes and infections. Previous approaches to nerve tracking have employed diffusion tensor imaging (DTI, [1, 2]), which is ...
The apolipoprotein E (apoE) genotype is an important genetic risk factor for Alzheimer's disease (AD). In the central nervous system (CNS), most apoE is produced by astrocytes and is present in unique high-density lipoprotein (HDL)-like particles that have ...
