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Modeling Unconstrained Self-Oriented Movements

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Soft microfabricated neural implants: a path towards translational implementation

Nicolas Vachicouras

Neuroprosthetics are a class of medical devices that aim to restore lost or impaired functions of the nervous system by electrical stimulation or recording of neural tissue. State of the art neural implants suffer today from a mechanical mismatch compared ...

EPFL2019

A neurostimulation system for central nervous stimulation (cns) and peripheral nervous stimulation (pns)

Silvestro Micera, Grégoire Courtine, Sophie Marie Marthe Wurth

The present disclosure relates to a neuromodulation and/or neurostimulation system comprising at least the following components: at least one sensing unit, at least control unit, at least one stimulation unit, at least one Central Nervous System (CNS) stim ...

2018

Framework for the Development of Neuroprostheses: From Basic Understanding by Sciatic and Median Nerves Models to Bionic Legs and Hands

Stanisa Raspopovic, Francesco Maria Petrini, Giacomo Valle, Marek Zelechowski

Neuroprostheses based on electrical stimulation are becoming a therapeutic reality, dramatically improving the life of disabled people. They are based on neural interfaces that are designed to create an intimate contact with neural cells. These devices spe ...

Ieee-Inst Electrical Electronics Engineers Inc2017

On the Use of Intraneural Transversal Electrodes to Develop Bidirectional Bionic Limbs

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

The development of more effective approaches for controlling dexterous hand prostheses is an important area of research currently addressed by several groups with the aim of improving the quality of life of amputees. It is particularly important to establi ...

Springer International Publishing Ag2017

Experience leaves a trace in the nervous system through plasticity. However, the exact meaning of the mnesic trace is poorly defined in current literature. This article provides a historical review of the term trace in neuroscience and psychoanalysis liter ...

Frontiers Research Foundation2017

SMN (Survival Motor Neuron) deficiency is the predominant cause of spinal muscular atrophy (SMA), a severe neurodegenerative disorder that can lead to progressive paralysis and death. Although SMN is required in every cell for proper RNA metabolism, the re ...

Academic Press Inc Elsevier Science2017

The Quest for a Bionic Hand

Silvestro Micera

Replacing a missing upper limb with a functional one is an ancient need and desire. The need for a versatile prosthetic limb with intuitive motor control and realistic sensory feedback is huge and its development is absolutely necessary for the near future ...

Springer International Publishing Ag2017

Detecting motion intention in stroke survivors using autonomic nervous system responses

Roger Gassert, Olivier Lambercy

Individuals with severe neurologic injuries often cannot participate in robotic rehabilitation because they do not retain sufficient residual motor control to initiate the robotic assistance. In these situations, brain- and body-computer interfaces have em ...

2015

Measurement of autophagy flux in the nervous system in vivo

Bernard Schneider

Accurate methods to measure autophagic activity in vivo in neurons are not available, and most of the studies are based on correlative and static measurements of autophagy markers, leading to conflicting interpretations. Autophagy is an essential homeostat ...

Nature Publishing Group2013

Materials for neural interfaces

Philippe Renaud

The treatment of disorders of the nervous system poses a major clinical challenge. Development of neuromodulation (i.e., interfacing electronics to nervous tissue to modulate its function) has provided patients with neuronal-related deficits a new tool to ...

2012