Publication

The excitatory neuronal microcircuit of the C2 column in the mouse primary somatosensory cortex

Related publications (52)

Frequency-dependent disynaptic inhibition in the pyramidal network: a ubiquitous pathway in the developing rat neocortex

Henry Markram, Rodrigo de Campos Perin, Thomas Berger, Gilad Silberberg

The general structure of the mammalian neocortex is remarkably similar across different cortical areas. Despite certain cytoarchitectural specializations and deviations from the general blueprint, the principal organization of the neocortex is relatively u ...

2009

The Excitatory Neuronal Network of the C2 Barrel Column in Mouse Primary Somatosensory Cortex

Carl Petersen, Juan-Carlos Sarria, Sandrine Lefort, Christian Tomm

Local microcircuits within neocortical columns form key determinants of sensory processing. Here, we investigate the excitatory synaptic neuronal network of an anatomically defined cortical column, the C2 barrel column of mouse primary somatosensory cortex ...

2009

Genetic manipulation, whole-cell recordings and functional imaging of the sensorimotor cortex of behaving mice

Carl Petersen

Sensory processing, sensorimotor integration and motor control are amongst the most basic functions of the brain and yet our understanding of how the underlying neuronal networks operate and contribute to behaviour is very limited. The relative simplicity ...

2009

Predicting Human Resting-State Functional Connectivity from structural Connectivity

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Leila Cammoun, Xavier Gigandet, Olaf Sporns

In the cerebral cortex, the activity levels of neuronal populations are continuously fluctuating. When neuronal activity, as measured using functional MRI (fMRI), is temporally coherent across 2 populations, those populations are said to be functionally co ...

2009

Internal body state influences topographical plasticity of sensory representations in the rat gustatory cortex

Riccardo Accolla

Primary sensory cortices are remarkably organized in spatial maps according to specific sensory features of the stimuli. These cortical maps can undergo plastic rearrangements after changes in afferent ("bottom-up") sensory inputs such as peripheral lesion ...

2008

Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic Acid animal model of autism

Henry Markram, Tania Rinaldi, Catherine Perrodin

The prefrontal cortex has been extensively implicated in autism to explain deficits in executive and other higher-order functions related to cognition, language, sociability and emotion. The possible changes at the level of the neuronal microcircuit are ho ...

2008

The functional organization of the barrel cortex

Carl Petersen

The tactile somatosensory pathway from whisker to cortex in rodents provides a well-defined system for exploring the link between molecular mechanisms, synaptic circuits, and behavior. The primary somatosensory cortex has an exquisite somatotopic map where ...

2007

Spatiotemporal dynamics of cortical sensorimotor integration in behaving mice

Carl Petersen, Rachel Aronoff

Tactile information is actively acquired and processed in the brain through concerted interactions between movement and sensation. Somatosensory input is often the result of self-generated movement during the active touch of objects, and conversely, sensor ...

2007

Dissociation of sustained attention from central executive functions: local activity and interregional connectivity in the theta range

Friedhelm Christoph Hummel

Human brain oscillatory activity was analysed in the electroencephalographic theta frequency range (4-7 Hz) while subjects executed complex sequential finger movements with varying task difficulty and memory load. Local frontal-midline theta activity was a ...

Wiley-Blackwell2007

Anatomical, physiological and molecular properties of Martinotti cells in the somatosensory cortex of the juvenile rat

Henry Markram, Gilad Silberberg, Yi Wang

Whole-cell patch-clamp recordings followed by histochemical staining and single-cell RT-PCR were obtained from 180 Martinotti interneurones located in layers II to VI of the somatosensory cortex of Wistar rats (P13-P16) in order to examine their anatomical ...

2004

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