Publication
Extra-cellular matrix (ECM) tethered morphogen gradients play an important role in tissue development and regeneration. There is currently only a limited set of model systems which can mimic these gradients in an artificial ECM-like environment. We have developed such a system that is able to stably immobilize a microfluidics-generated protein gradient on a poly(ethylene) glycol (PEG) hydrogel. After patterning, the hydrogel can be released from the chip and be directly used for cell culture.
Philippe Renaud, Sandro Carrara, Francesca Stradolini, Tugba Kilic, Fatemeh Navaee
Christian Heinis, Xudong Kong, Jonas Alfred Karl Wilbs, Jeremy Touati, Michal Sabisz, Alice Baumann
Raquel Filipa Penacho Parreira