StainingStaining is a technique used to enhance contrast in samples, generally at the microscopic level. Stains and dyes are frequently used in histology (microscopic study of biological tissues), in cytology (microscopic study of cells), and in the medical fields of histopathology, hematology, and cytopathology that focus on the study and diagnoses of diseases at the microscopic level. Stains may be used to define biological tissues (highlighting, for example, muscle fibers or connective tissue), cell populations (classifying different blood cells), or organelles within individual cells.
Digital signal processorA digital signal processor (DSP) is a specialized microprocessor chip, with its architecture optimized for the operational needs of digital signal processing. DSPs are fabricated on MOS integrated circuit chips. They are widely used in audio signal processing, telecommunications, , radar, sonar and speech recognition systems, and in common consumer electronic devices such as mobile phones, disk drives and high-definition television (HDTV) products. The goal of a DSP is usually to measure, filter or compress continuous real-world analog signals.
Electrical engineering technologyElectrical/Electronics engineering technology (EET) is an engineering technology field that implements and applies the principles of electrical engineering. Like electrical engineering, EET deals with the "design, application, installation, manufacturing, operation or maintenance of electrical/electronic(s) systems." However, EET is a specialized discipline that has more focus on application, theory, and applied design, and implementation, while electrical engineering may focus more of a generalized emphasis on theory and conceptual design.
Index of electrical engineering articlesThis is an alphabetical list of articles pertaining specifically to electrical and electronics engineering. For a thematic list, please see List of electrical engineering topics. For a broad overview of engineering, see List of engineering topics. For biographies, see List of engineers.
Primary and secondary antibodiesPrimary and secondary antibodies are two groups of antibodies that are classified based on whether they bind to antigens or proteins directly or target another (primary) antibody that, in turn, is bound to an antigen or protein. A primary antibody can be very useful for the detection of biomarkers for diseases such as cancer, diabetes, Parkinson’s and Alzheimer’s disease and they are used for the study of absorption, distribution, metabolism, and excretion (ADME) and multi-drug resistance (MDR) of therapeutic agents.
History of computing hardware (1960s–present)The history of computing hardware starting at 1960 is marked by the conversion from vacuum tube to solid-state devices such as transistors and then integrated circuit (IC) chips. Around 1953 to 1959, discrete transistors started being considered sufficiently reliable and economical that they made further vacuum tube computers uncompetitive. Metal–oxide–semiconductor (MOS) large-scale integration (LSI) technology subsequently led to the development of semiconductor memory in the mid-to-late 1960s and then the microprocessor in the early 1970s.
Classes of computersComputers can be classified, or typed, in many ways. Some common classifications of computers are given below. |- |style="text-align: left;"|Notes: Microcomputers became the most common type of computer in the late 20th century. The term “microcomputer” was introduced with the advent of systems based on single-chip microprocessors. The best-known early system was the Altair 8800, introduced in 1975. The term "microcomputer" has practically become an anachronism as it has fallen into disuse.
Aequorea victoriaAequorea victoria, also sometimes called the crystal jelly, is a bioluminescent hydrozoan jellyfish, or hydromedusa, that is found off the west coast of North America. The species is best known as the source of aequorin (a photoprotein), and green fluorescent protein (GFP); two proteins involved in bioluminescence. Their discoverers, Osamu Shimomura and colleagues, won the 2008 Nobel Prize in Chemistry for their work on GFP.
Papanicolaou stainPapanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942. The Papanicolaou stain is one of the most widely used stains in cytology, where it is used to aid pathologists in making a diagnosis. Although most notable for its use in the detection of cervical cancer in the Pap test or Pap smear, it is also used to stain non-gynecological specimen preparations from a variety of bodily secretions and from small needle biopsies of organs and tissues.
Negative stainIn microscopy, negative staining is an established method, often used in diagnostic microscopy, for contrasting a thin specimen with an optically opaque fluid. In this technique, the background is stained, leaving the actual specimen untouched, and thus visible. This contrasts with positive staining, in which the actual specimen is stained. Bright-field microscopy For bright-field microscopy, negative staining is typically performed using a black ink fluid such as nigrosin and India ink.
