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Superparamagnetic Nanoparticles as a Powerful Systems Biology. Characterization Tool in the Physiological Context
Related publications (33)
New and improved methods for integrated models of metabolism and gene expression
The beginning of the 21st century was marked by the advent of disruptive technologies, which ushered an era of groundbreaking advances in fundamental sciences, carried by the great pace at which computational capabilities spread and evolved. But the new ce ...
EPFL2021Neighborhood watch: tools for defining locale-dependent subproteomes and their contextual signaling activities
Transient associations between numerous organelles-e.g., the endoplasmic reticulum and the mitochondria-forge highly-coordinated, particular environments essential for cross-compartment information flow. Our perspective summarizes chemical-biology tools th ...
ROYAL SOC CHEMISTRY2020Empowering Global Chemical Biology at the Dawn of the New Decade
On January 22-24, 2020, scientific luminaries across the far-flung corners of chemical biology gathered in Geneva, Switzerland, to deliver their latest and greatest discoveries in the field. Generously supported by the Swiss National Science Foundation (SN ...
AMER CHEMICAL SOC2020MPGM: Scalable and Accurate Multiple Network Alignment
Matthias Grossglauser, Ehsan Kazemi
Protein-protein interaction (PPI) network alignment is a canonical operation to transfer biological knowledge among species. The alignment of PPI-networks has many applications, such as the prediction of protein function, detection of conserved network mot ...
IEEE COMPUTER SOC2020Monobodies as enabling tools for structural and mechanistic biology
Monobodies, built with the scaffold of the fibronectin type III domain, are among the most well-established synthetic binding proteins. They promote crystallization of challenging molecular systems. They have strong tendency to bind to functional sites and ...
CURRENT BIOLOGY LTD2020Analysis of cellular and drug action mechanisms in the malaria parasites using systems biology approaches
Malaria puts at risk of infection half of the world population and still kills around half a million people every year. The rapid and worrisome rise of drug-resistant malaria parasites hinders the treatment of malaria and calls for a global collaboration t ...
EPFL2018ETFL: A Formulation of ME-Models Accounting for Expression and Thermodynamics in Constraint-Based Models
Since flux balance analysis (FBA) has been introduced in Systems Biology, several attempts have been made at supplementing it with expression data [1-3]. With the notable exception of O’Brien et al. [1], none of them account directly for the enzyme product ...
2018Computational methods and modeling of cellular function for the optimization of protein production and the study of cellular disease states
Systems biology is a multidisciplinary field that weaves together all the basic sciences through the use of computational and bioinformatics tools, to provide a more integrative view of the complex molecular interactions taking place within and among cells ...
EPFL2017Principles of Systems Biology, No. 11
Vassily Hatzimanikatis, Jasmin Maria Hafner, Noushin Hadadi, Laurent Potvin-Trottier
This month: AI that learns patterns and facts, new protein-RNA and protein-protein relationships, engineering signaling and metabolism, and more variants of Cas9. ...
Cell Press2016