Prediction of bone density around orthopedic implants delivering bisphosphonate
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Bisphosphonates are known for their strong inhibitory effect on bone resorption. Their influence on bone formation however is less clear. In this study we investigated the spatio-temporal effect of locally delivered Zoledronate on peri-implant bone formati ...
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Background: orthopaedic surgeons often face clinical situations where improved screw holding power in cancellous bone is needed. Injectable calcium phosphate cements are one option to enhance fixation. Methods: paired screw pullout tests were undertaken in ...
Implanted rat bones play a key role in studies involving fracture healing, bone diseases or drugs delivery among other themes. In most of these studies the implants integration also depends on the animal daily activity and musculoskeletal loads, which affe ...
The hip is one of the most injured joint in the body with ageing. Osteoarthritis and degenerative diseases often lead to the necessity of a total hip arthroplasty in order to reduce pain and increase mobility. The advantage of cementless implants resides i ...
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A good implant primary stability is closely associated with long-term success of total hip arthroplasty. Excessive interfacial micromotion around the femoral component after cementless hip replacement is related to aseptic loosening of the stem and affects ...
Osteoporosis is a major health problem in our aging society. This metabolic disease, which is characterized by a deterioration of the bone microarchitecture and a significant loss of bone mass, is affecting a rising number of mostly elderly patients. The m ...
