Publication

Mineral metabolism and bone mass at peripheral and axial skeleton in diabetes mellitus

Related publications (54)

JewelPUMP (TM) by Debiotech S.A.: Insulin Temperature Measurement Study

For type 1 Diabetes, insulin injection therapy is the most used treatment today, and insulin pumps are surely the most accurate therapeutic strategy. The insulin use temperature has to not exceed 37°C to prevent unwanted degradation and loss of function. T ...

2011

Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia

Daniel Constam, Marine Marie Kraus, Anne Grapin-Botton

Bicaudal C homologue 1 (Bicc1) knockout in mice causes polycystic kidney disease and pancreas development defects, including a reduction in insulin-producing β-cells and ensuing diabetes. We therefore screened 137 patients with renal abnormalities or assoc ...

2011

High-Resolution Magnetic Resonance Imaging Quantitatively Detects Individual Pancreatic Islets

Rolf Gruetter, Riikka Immonen, Christine Nabuurs

OBJECTIVE-We studied whether manganese-enhanced high-field magnetic resonance (MR) imaging (MEHFMRI) could quantitatively detect individual islets in situ and in vivo and evaluate changes in a model of experimental diabetes. ...

2011

Calcareous sponge biomineralization: Ultrastructural and compositional heterogeneity of spicules in Leuconia johnstoni Carter, 1871

Anders Meibom, Jaroslaw Hubert Stolarski, Isabelle Domart-Coulon, Christophe Kopp

In contrast to siliceous sponge spicules, the biomineralization in calcareous sponges is poorly understood. In particular, the existence of a differentiated central core in calcareous spicules is still controversial. Here we combine high-spatial resolution ...

2011

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

Kamiar Aminian, Stéphane Armand

Gait characteristics and balance are altered in diabetic patients. Little is known about possible treatment strategies. This study evaluates the effect of a specific training programme on gait and balance of diabetic patients. ...

2010

An exercise intervention to improve diabetic patients' gait in a real-life environment

Kamiar Aminian, Stéphane Armand

Aims: Gait characteristics and balance are altered in diabetic individuals. Little is known about possible treatment strategies. This study evaluated the effect of a specific training program on diabetic patients' gait. ...

Elsevier2010

The prolyl-aminodipeptidases and their inhibitors as therapeutic targets for fibrogenic disorders

Sandrine Gerber

Many biologically active peptides are protected from general proteolytic degradation by evolutionary conserved prolines (Pro), due to conformational constraints imposed by the Pro residue. Thus the biological importance of prolyl-specific peptidases points ...

2009

Induction of brain aquaporin 9 (AQP9) in catecholaminergic neurons in diabetic rats

Pierre Magistretti, Jean-Marie Petit

Aquaporin 9 facilitates the diffusion of water but also glycerol and monocarboxylates, known as brain energy substrates. AQP9 was recently observed in catecholaminergic neurons that are implicated in energy homeostasis and also possibly in neuroendocrine e ...

2008

Visceral obesity is associated with high levels of serum squalene

Johan Auwerx

OBJECTIVE: To investigate the impact of visceral obesity on cholesterol metabolism in normoglycemic offspring of patients with type 2 diabetes. RESEARCH METHODS AND PROCEDURES: The proportion of intra-abdominal fat (IAF) was measured by abdominal computer ...

2006

Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: an ex vivo gene therapy approach

Didier Trono

AIMS/HYPOTHESIS: We examined a clinical model of ex vivo transdifferentiation of primary adult hepatocytes to insulin-secreting cells for the treatment of type 1 diabetes. MATERIALS AND METHODS: Isolated rat hepatocytes were transduced in primary culture w ...

Springer Verlag2006

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