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Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E epsilon 4 allele

Related publications (34)

CDKL5 sculpts functional callosal connectivity to promote cognitive flexibility

Functional and structural connectivity alterations in short- and long-range projections have been reported across neurodevelopmental disorders (NDD). Interhemispheric callosal projection neurons (CPN) represent one of the major long-range projections in th ...

SPRINGERNATURE2023

Theta oscillations and minor hallucinations in Parkinson’s disease reveal decrease in frontal lobe functions and later cognitive decline

Olaf Blanke, Fosco Bernasconi

Cognitive decline and hallucinations are common and debilitating non-motor symptoms, usually occurring during later phases of Parkinson’s disease (PD). Minor hallucinations (MH) appear early in the disease course and have been suggested to predict cognitiv ...

2023

Corpus callosum structural characteristics in very preterm children and adolescents: Developmental trajectory and relationship to cognitive functioning

Dimitri Nestor Alice Van De Ville, Vanessa Siffredi

Previous studies suggest that structural alteration of the corpus callosum, i.e., the largest white matter commissural pathway, occurs after a preterm birth in the neonatal period and lasts across development. The present study aims to unravel corpus callo ...

ELSEVIER SCI LTD2023

Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset

Christopher Clark

Alzheimer's disease (AD) is the most frequent neurodegenerative disease with an increasing prevalence in industrialized, aging populations. AD susceptibility has an established genetic basis which has been the focus of a large number of genome-wide associa ...

FRONTIERS MEDIA SA2022

Is there an association between cognitive and visual decline?

Michael Herzog, Simona Adele Garobbio

Cognitive and visual abilities decline with age. Recently, it has been suggested that the risk to suffer from dementia is associated with decreased visual acuity. Two theories, the sensory deprivation theory (stating that visual impairments cause cognitive ...

2022

Determining patterns of post-stroke motor recovery through longitudinal multimodal MRI: A step towards patient stratification

Julia Brügger

Motivated by the need for a better understanding of post-stroke recovery and new biomarkers to improve stroke patient stratification and outcomes, this thesis investigated structure-function coupling and its role in post-stroke recovery. Furthermore, in or ...

EPFL2022

No Common Factor Underlying Decline of Visual Abilities in Mild Cognitive Impairment

Michael Herzog, Simona Adele Garobbio

Introduction Recent work has shown an association between cognitive and visual impairments and two main theories were advanced, namely the sensory deprivation and the common cause theories. Most studies considered only basic visual functions such as visual ...

2022

Brain connectivity and metacognition in persons with subjective cognitive decline (COSCODE): rationale and study design

Ileana Ozana Jelescu

Background Subjective cognitive decline (SCD) is the subjective perception of a decline in memory and/or other cognitive functions in the absence of objective evidence. Some SCD individuals however may suffer from very early stages of neurodegenerative dis ...

2021

Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer's disease pathology and clinical disease progression

Bénédicte Marie Maréchal, Jonas Richiardi, Christopher Clark

BackgroundTo assess the performance of plasma neurofilament light (NfL) and phosphorylated tau 181 (p-tau181) to inform about cerebral Alzheimer's disease (AD) pathology and predict clinical progression in a memory clinic setting.MethodsPlasma NfL and p-ta ...

BMC2021

The perspectives of mapping and monitoring of the sense of self in neurosurgical patients

Olaf Blanke, Bruno Herbelin, Hyeongdong Park, Sophie Jacqueline Andrée Betka, Pavo Orepic, Sixto Luis Alcoba Banqueri, Giannina Rita Iannotti

Surgical treatment of tumors, epileptic foci or of vascular origin, requires a detailed individual pre-surgical workup and intra-operative surveillance of brain functions to minimize the risk of post-surgical neurological deficits and decline of quality of ...

SPRINGER WIEN2021

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