Renesas Electronicsis a Japanese semiconductor manufacturer headquartered in Tokyo, Japan, initially incorporated in 2002 as Renesas Technology, the consolidated entity of the semiconductor units of Hitachi and Mitsubishi excluding their dynamic random-access memory (DRAM) businesses, to which NEC Electronics merged in 2010, resulting in a minor change in the corporate name and logo to as it is now. In the 2000s to early 2010s, Renesas had been one of the six largest semiconductor companies in the world.
Hybridization probeIn molecular biology, a hybridization probe (HP) is a fragment of DNA or RNA of usually 15–10000 nucleotide long which can be radioactively or fluorescently labeled. HP can be used to detect the presence of nucleotide sequences in analyzed RNA or DNA that are complementary to the sequence in the probe. The labeled probe is first denatured (by heating or under alkaline conditions such as exposure to sodium hydroxide) into single stranded DNA (ssDNA) and then hybridized to the target ssDNA (Southern blotting) or RNA (northern blotting) immobilized on a membrane or in situ.
Samsung ElectronicsSamsung Electronics Co., Ltd. (, sometimes shortened to SEC and stylized as SΛMSUNG) is a South Korean multinational major appliance and consumer electronics corporation headquartered in Yeongtong-gu, Suwon, South Korea. It is currently the pinnacle of the Samsung chaebol, accounting for 70% of the group's revenue in 2012. However, Lee Jae-yong has stated his intentions on making sure his children would not inherit significant Samsung Electronics positions, which would significantly change the chaebol's inner workings.
Intel 4004The Intel 4004 is a 4-bit central processing unit (CPU) released by Intel Corporation in 1971. Sold for US60(,449.43 in 2023), it was the first commercially produced microprocessor, and the first in a long line of Intel CPUs. The 4004 was the first significant example of large scale integration, showcasing the superiority of the MOS silicon gate technology (SGT). Compared to the incumbent technology, the SGT integrated on the same chip area twice the number of transistors with five times the operating speed. Integrated circuit layout design protectionLayout designs (topographies) of integrated circuits are a field in the protection of intellectual property. In United States intellectual property law, a "mask work" is a two or three-dimensional layout or topography of an integrated circuit (IC or "chip"), i.e. the arrangement on a chip of semiconductor devices such as transistors and passive electronic components such as resistors and interconnections.
PrototypeA prototype is an early sample, model, or release of a product built to test a concept or process. It is a term used in a variety of contexts, including semantics, design, electronics, and software programming. A prototype is generally used to evaluate a new design to enhance precision by system analysts and users. Prototyping serves to provide specifications for a real, working system rather than a theoretical one. In some design workflow models, creating a prototype (a process sometimes called materialization) is the step between the formalization and the evaluation of an idea.
Optical heterodyne detectionOptical heterodyne detection is a method of extracting information encoded as modulation of the phase, frequency or both of electromagnetic radiation in the wavelength band of visible or infrared light. The light signal is compared with standard or reference light from a "local oscillator" (LO) that would have a fixed offset in frequency and phase from the signal if the latter carried null information. "Heterodyne" signifies more than one frequency, in contrast to the single frequency employed in homodyne detection.
Fluorescence in situ hybridizationFluorescence in situ hybridization (FISH) is a molecular cytogenetic technique that uses fluorescent probes that bind to only particular parts of a nucleic acid sequence with a high degree of sequence complementarity. It was developed by biomedical researchers in the early 1980s to detect and localize the presence or absence of specific DNA sequences on chromosomes. Fluorescence microscopy can be used to find out where the fluorescent probe is bound to the chromosomes.
Comparative genomic hybridizationComparative genomic hybridization (CGH) is a molecular cytogenetic method for analysing copy number variations (CNVs) relative to ploidy level in the DNA of a test sample compared to a reference sample, without the need for culturing cells. The aim of this technique is to quickly and efficiently compare two genomic DNA samples arising from two sources, which are most often closely related, because it is suspected that they contain differences in terms of either gains or losses of either whole chromosomes or subchromosomal regions (a portion of a whole chromosome).
Electronic system-level design and verificationElectronic system level (ESL) design and verification is an electronic design methodology, focused on higher abstraction level concerns. The term Electronic System Level or ESL Design was first defined by Gartner Dataquest, an EDA-industry-analysis firm, on February 1, 2001. It is defined in ESL Design and Verification as: "the utilization of appropriate abstractions in order to increase comprehension about a system, and to enhance the probability of a successful implementation of functionality in a cost-effective manner.