Cell-mediated immunityCell-mediated immunity or cellular immunity is an immune response that does not involve antibodies. Rather, cell-mediated immunity is the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen. In the late 19th century Hippocratic tradition medicine system, the immune system was imagined into two branches: humoral immunity, for which the protective function of immunization could be found in the humor (cell-free bodily fluid or serum) and cellular immunity, for which the protective function of immunization was associated with cells.
Weight (representation theory)In the mathematical field of representation theory, a weight of an algebra A over a field F is an algebra homomorphism from A to F, or equivalently, a one-dimensional representation of A over F. It is the algebra analogue of a multiplicative character of a group. The importance of the concept, however, stems from its application to representations of Lie algebras and hence also to representations of algebraic and Lie groups. In this context, a weight of a representation is a generalization of the notion of an eigenvalue, and the corresponding eigenspace is called a weight space.
White blood cellWhite blood cells, also called leukocytes or leucocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. White blood cells include three main subtypes; granulocytes, lymphocytes and monocytes. White cells is most preferred rather than the, white blood cells, because, they spend most of their time in the lymph or plasma. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells.
Stem-cell nicheStem-cell niche refers to a microenvironment, within the specific anatomic location where stem cells are found, which interacts with stem cells to regulate cell fate. The word 'niche' can be in reference to the in vivo or in vitro stem-cell microenvironment. During embryonic development, various niche factors act on embryonic stem cells to alter gene expression, and induce their proliferation or differentiation for the development of the fetus.
Fundamental representationIn representation theory of Lie groups and Lie algebras, a fundamental representation is an irreducible finite-dimensional representation of a semisimple Lie group or Lie algebra whose highest weight is a fundamental weight. For example, the defining module of a classical Lie group is a fundamental representation. Any finite-dimensional irreducible representation of a semisimple Lie group or Lie algebra can be constructed from the fundamental representations by a procedure due to Élie Cartan.
Chimera (genetics)A genetic chimerism or chimera (kaɪˈmɪərə,_kə- ) is a single organism composed of cells with more than one distinct genotype. In animals and human chimeras, this means an individual derived from two or more zygotes, which can include possessing blood cells of different blood types, subtle variations in form (phenotype) and, if the zygotes were of differing sexes, then even the possession of both female and male sex organs. Animal chimeras are produced by the merger of two (or more) embryos.
Natural killer cellNatural killer cells, also known as NK cells or large granular lymphocytes (LGL), are a type of cytotoxic lymphocyte critical to the innate immune system that belong to the rapidly expanding family of known innate lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. The role of NK cells is analogous to that of cytotoxic T cells in the vertebrate adaptive immune response. NK cells provide rapid responses to virus-infected cell and other intracellular pathogens acting at around 3 days after infection, and respond to tumor formation.
TransfectionTransfection is the process of deliberately introducing naked or purified nucleic acids into eukaryotic cells. It may also refer to other methods and cell types, although other terms are often preferred: "transformation" is typically used to describe non-viral DNA transfer in bacteria and non-animal eukaryotic cells, including plant cells. In animal cells, transfection is the preferred term as transformation is also used to refer to progression to a cancerous state (carcinogenesis) in these cells.
FluorescenceFluorescence is the emission of light by a substance that has absorbed light or other electromagnetic radiation. It is a form of luminescence. In most cases, the emitted light has a longer wavelength, and therefore a lower photon energy, than the absorbed radiation. A perceptible example of fluorescence occurs when the absorbed radiation is in the ultraviolet region of the electromagnetic spectrum (invisible to the human eye), while the emitted light is in the visible region; this gives the fluorescent substance a distinct color that can only be seen when the substance has been exposed to UV light.
Compact groupIn mathematics, a compact (topological) group is a topological group whose topology realizes it as a compact topological space (when an element of the group is operated on, the result is also within the group). Compact groups are a natural generalization of finite groups with the discrete topology and have properties that carry over in significant fashion. Compact groups have a well-understood theory, in relation to group actions and representation theory. In the following we will assume all groups are Hausdorff spaces.
