Biological networkA biological network is a method of representing systems as complex sets of binary interactions or relations between various biological entities. In general, networks or graphs are used to capture relationships between entities or objects. A typical graphing representation consists of a set of nodes connected by edges. As early as 1736 Leonhard Euler analyzed a real-world issue known as the Seven Bridges of Königsberg, which established the foundation of graph theory. From the 1930's-1950's the study of random graphs were developed.
Systematic samplingIn survey methodology, systematic sampling is a statistical method involving the selection of elements from an ordered sampling frame. The most common form of systematic sampling is an equiprobability method. In this approach, progression through the list is treated circularly, with a return to the top once the list ends. The sampling starts by selecting an element from the list at random and then every kth element in the frame is selected, where k, is the sampling interval (sometimes known as the skip): this is calculated as: where n is the sample size, and N is the population size.
Snowball samplingIn sociology and statistics research, snowball sampling (or chain sampling, chain-referral sampling, referral sampling) is a nonprobability sampling technique where existing study subjects recruit future subjects from among their acquaintances. Thus the sample group is said to grow like a rolling snowball. As the sample builds up, enough data are gathered to be useful for research. This sampling technique is often used in hidden populations, such as drug users or sex workers, which are difficult for researchers to access.
Phosphoenolpyruvate carboxykinasePhosphoenolpyruvate carboxykinase (, PEPCK) is an enzyme in the lyase family used in the metabolic pathway of gluconeogenesis. It converts oxaloacetate into phosphoenolpyruvate and carbon dioxide. It is found in two forms, cytosolic and mitochondrial. In humans there are two isoforms of PEPCK; a cytosolic form (SwissProt P35558) and a mitochondrial isoform (SwissProt Q16822) which have 63.4% sequence identity. The cytosolic form is important in gluconeogenesis.
