Denis Duboule, Alexandre Gauthier Aurèle Mayran, Hocine Rekaik, Lucille Delisle, Aurélie Hintermann, Célia Corinne Renée Bochaton
Temporal activation of Hox genes in mouse pseudo-embryos in vitro initiates at the anterior part of the cluster and is accompanied by asymmetric loading of cohesin. Posterior CTCF sites then successively act as transient insulators, regulating the timed tr ...
NATURE PORTFOLIO2023