Distribution of the monocarboxylate transporter MCT2 in human cerebral cortex: an immunohistochemical study
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Neocortical microcircuits of primary sensory cortices play prominent roles in processing peripheral input. The same cortical microcircuits are also spontaneously active, which profoundly influences sensory processing. In this issue of Neuron, Sakata and Ha ...
Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways. Using diffusion spectrum imaging we noninvasively map these pathways within and across cort ...
Human cerebral cortex contains an uncertain number of structurally segregated regions interconnected by a dense network of axonal pathways. Using DSI, we map these pathways in individual human subjects. An analysis of the resulting large-scale structural b ...
Neuronal migration is a fundamental component of brain development whose failure is associated with various neurological and psychiatric disorders. Reelin is essential for the stereotypical inside-out sequential lamination of the neocortex, but the molecul ...
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Recent studies at high magnetic fields using the phase of gradient-echo MR images have shown the ability to unveil cortical substructure in the human brain. To investigate the contrast mechanisms in phase imaging, this study extends, for the first time, ph ...
Context Two sets of findings predict smaller cerebral cortical gray matter volume in adult posttraumatic stress disorder (PTSD). Measures of intracranial tissue volume and cerebral tissue volume have been observed to be smaller in adolescents with maltreat ...
Controversy exists regarding the site where anesthetics act in the brain to produce sedation and unconsciousness. Actions in the cerebral cortex and thalamus are likely, although the relative importance of each site is unclear. We used in computo modeling ...
BACKGROUND: We have used a computational model of the thalamocortical system to investigate the effects of a GABAergic anesthetic (etomidate) on cerebral cortical and thalamic neuronal function. We examined the effects of phasic an tonic inhibition, as wel ...
Phosphate and tensin homologue deleted on chromosome 10 (PTEN) is a tumor suppressor gene inactivated in numerous sporadic cancers, including melanomas. To analyze Pten functions in melanocytes, we used the Cre-loxP system to delete Pten specifically in mu ...
