Glucose 6-phosphateGlucose 6-phosphate (G6P, sometimes called the Robison ester) is a glucose sugar phosphorylated at the hydroxy group on carbon 6. This dianion is very common in cells as the majority of glucose entering a cell will become phosphorylated in this way. Because of its prominent position in cellular chemistry, glucose 6-phosphate has many possible fates within the cell. It lies at the start of two major metabolic pathways: glycolysis and the pentose phosphate pathway.
Type 1 diabetesType 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that originates when cells that make insulin (beta cells) are destroyed by the immune system. Insulin is a hormone required for the cells to use blood sugar for energy and it helps regulate glucose levels in the bloodstream. Before treatment this results in high blood sugar levels in the body. The common symptoms of this elevated blood sugar are frequent urination, increased thirst, increased hunger, weight loss, and other serious complications.
Dual polyhedronIn geometry, every polyhedron is associated with a second dual structure, where the vertices of one correspond to the faces of the other, and the edges between pairs of vertices of one correspond to the edges between pairs of faces of the other. Such dual figures remain combinatorial or abstract polyhedra, but not all can also be constructed as geometric polyhedra. Starting with any given polyhedron, the dual of its dual is the original polyhedron. Duality preserves the symmetries of a polyhedron.
Cable theoryClassical cable theory uses mathematical models to calculate the electric current (and accompanying voltage) along passive neurites, particularly the dendrites that receive synaptic inputs at different sites and times. Estimates are made by modeling dendrites and axons as cylinders composed of segments with capacitances and resistances combined in parallel (see Fig. 1). The capacitance of a neuronal fiber comes about because electrostatic forces are acting through the very thin lipid bilayer (see Figure 2).
120-cellIn geometry, the 120-cell is the convex regular 4-polytope (four-dimensional analogue of a Platonic solid) with Schläfli symbol {5,3,3}. It is also called a C120, dodecaplex (short for "dodecahedral complex"), hyperdodecahedron, polydodecahedron, hecatonicosachoron, dodecacontachoron and hecatonicosahedroid. The boundary of the 120-cell is composed of 120 dodecahedral cells with 4 meeting at each vertex. Together they form 720 pentagonal faces, 1200 edges, and 600 vertices.
Truncated 24-cellsIn geometry, a truncated 24-cell is a uniform 4-polytope (4-dimensional uniform polytope) formed as the truncation of the regular 24-cell. There are two degrees of truncations, including a bitruncation. The truncated 24-cell or truncated icositetrachoron is a uniform 4-dimensional polytope (or uniform 4-polytope), which is bounded by 48 cells: 24 cubes, and 24 truncated octahedra. Each vertex joins three truncated octahedra and one cube, in an equilateral triangular pyramid vertex figure.
