Publication
VIP neurons in the cerebral cortex
Related publications (32)
Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1
Carl Petersen, Graham Knott, Catherine Maclachlan, Seung-Hee Lee
Somatostatin (SST) is a neuropeptide expressed in a major subtype of GABAergic interneurons in the cortex. Despite abundant expression of SST and its receptors, their modulatory function in cortical processing remains unclear. Here, we found that SST appli ...
2020Layer, cell-type and pathway-specific thalamocortical input to mouse somatosensory cortex
In the mouse whisker system, sensory information is relayed to the whisker somatosensory cortex by two major thalamic nuclei, the ventral posterior medial nucleus (VPM) and the posterior medial nucleus (POM). While the cortical axonal innervation pattern o ...
EPFL2018Two-photon calcium imaging of neocortical projection neurons in whisker somatosensory cortex during goal-directed sensorimotor learning
Abstract
Excitatory projection neurons of the neocortex are thought to play important roles in per-ceptual and cognitive functions of the brain by directly connecting diverse cortical and subcortical areas. However, many aspects of the anatomical and func ...
EPFL2018Dependence of Hippocampal Function on ERR gamma-Regulated Mitochondrial Metabolism
Neurons utilize mitochondrial oxidative phosphorylation (OxPhos) to generate energy essential for survival, function, and behavioral output. Unlike most cells that burn both fat and sugar, neurons only burn sugar. Despite its importance, how neurons meet t ...
Cell Press2015Cortical Interneuron Loss and Symptom Heterogeneity in Huntington Disease
Objective: The cellular basis of variable symptoms in Huntington disease (HD) is unclear. One important possibility is that degeneration of the interneurons in the cerebral cortex, which play a critical role in modulating cortical output to the basal gangl ...
Wiley-Blackwell2014Deconstructing the Default: Cortical subdivision of the Default Mode/Intrinsic System During Self-Related Processing
Recent brain imaging research has highlighted a new global system of areas termed the Default Mode network (DM), which appears to specialize in intrinsically oriented functions. However, it is still unresolved to what extent this system contains functional ...
Wiley-Blackwell2014Regulation of Neurotrophic Factors and Energy Metabolism by Antidepressants in Astrocytes
Pierre Magistretti, Jean-Luc Martin, Igor Allaman
There is growing evidence that astrocytes are involved in the neuropathology of major depression. In particular, decreases in glial cell density observed in the cerebral cortex of individuals with major depressive disorder are accompanied by a reduction of ...
Bentham Science Publishers2013Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo
The study of human cortical development has major implications for brain evolution and diseases but has remained elusive due to paucity of experimental models. Here we found that human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), ...
Cell Press2013PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity
Liliane Glauser, Elpida Tsika, Darren Moore, Sarah Catherine Sonnay, Klodjan Stafa, Alzbeta Trancikova, David Ramonet Jimenez, Agata Podhajska
Mutations in the ATP13A2 gene (PARK9, OMIM 610513) cause autosomal recessive, juvenile-onset Kufor-Rakeb syndrome and early-onset parkinsonism. ATP13A2 is an uncharacterized protein belonging to the P-5-type ATPase subfamily that is predicted to regulate t ...
Oxford University Press2012Synergistic NGF/B27 Gradients Position Synapses Heterogeneously in 3D Micropatterned Neural Cultures
Philippe Renaud, Dominique Zosso, Ana Valero, Anja Kunze
Native functional brain circuits show different numbers of synapses (synaptic densities) in the cerebral cortex. Until now, different synaptic densities could not be studied in vitro using current cell culture methods for primary neurons. Herein, we presen ...
Public Library of Science2011