Collinear contextual suppression in schizophrenic patients
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Background: Earlier contributions have documented significant changes in sensory, attention-related endogenous event-related potential (ERP) components and theta band oscillatory responses during working memory activation in patients with schizophrenia. In ...
A fundamental trait of the human self is its continuum experience of space and time. Perceptual aberrations of this spatial and temporal continuity is a major characteristic of schizophrenia spectrum disturbances – including schizophrenia, schizotypal pers ...
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The obvious symptoms of schizophrenia are of cognitive and psychopathological nature. However, schizophrenia affects also visual processing which becomes particularly evident when stimuli are presented for short durations and are followed by a masking stim ...
Visual backward masking (VBM) deficits are a potential endophenotype of schizophrenia. VBM deficits were found in schizophrenic patients, in their unaffected relatives, and in healthy students scoring high in "cognitive disorganisation" (CD; Cappe et al., ...
Statistical models of neural activity are at the core of the field of modern computational neuroscience. The activity of single neurons has been modeled to successfully explain dependencies of neural dynamics to its own spiking history, to external stimuli ...
Sustained attention deficits measured by the Continuous Performance Test (CPT) have been reportedly proposed as an endophenotype of schizophrenia. One requirement for an endophenotype is that unaffected first-order relatives must show deteriorated performa ...
In visual backward masking, a briefly presented target is followed by a mask, which impairs target discrimination. Backward masking is strongly impaired in schizophrenic patients and their unaffected relatives. We found that masking deficits correlated wel ...
Endophenotypes (i.e. stable and heritable markers of the illness) are one of the promising tools to understand the pathological mechanisms underlying schizophrenia. We recently showed that deficits in visual backward masking (VBM) meet the criteria for an ...
Statistical models of neural activity are integral to modern neuroscience. Recently interest has grown in modeling the spiking activity of populations of simultaneously recorded neurons to study the effects of correlations and functional connectivity on ne ...
