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We describe a set of probability distributions, dubbed compressible priors, whose independent and identically distributed (iid) realizations result in p-compressible signals. A signal x in R^N is called p-compressible with magnitude R if its sorted coeffic ...
Collagen is highly conserved across species and has been used extensively for tissue regeneration; however, its mechanical properties are limited. A recent advance using plastic compression of collagen gels to achieve much higher concentrations significant ...
This thesis is intended to contribute to the field of biomechanics of growth and remodeling of arteries. The work focuses particularly on growth and remodeling caused by sustained hypertension, increased blood flow, and ageing. A structure-based constituti ...
The nucleus pulposus of the intervertebral disc is a gelatinous viscous hydrogel that has an essential role in the mechanics of the intervertebral disc joint. The viscoelastic properties of the nucleus pulposus significantly change in the course of time an ...
In the 90ies the IBOIS-EPFL developed a new kind of shell structure. The ribs were made with simple boards waved together to form a spatial rib shell. However, the engineer currently does not have any effective method to calculate these kinds of spatial st ...
Primary lymphedema is a congenital pathology of dysfunctional lymphatic drainage characterized by swelling of the limbs, thickening of the dermis, and fluid and lipid accumulation in the underlying tissue. Two mouse models of primary lymphedema, the Chy mo ...
Biologic tissues such as the annulus fibrosus of the intervertebral disc present viscoelastic and anisotropic responses to mechanical loading. The objective of this semester project is to propose a method to implement routinely anisotropy-modelling in the ...
The passive biomechanical behavior of blood vessels is generally modeled by a parallel arrangement of elastin and collagen, with collagen recruitment depending on vessel strain. We experimentally determined the collagen recruitment distribution using confo ...
The purpose of the study is to characterize the main features of the anisotropic mechanical behaviour of a shale (Opalinus Clay), and to identify an anisotropic constitutive framework adapted to the response of the material under mechanical perturbations. ...
Myofibroblasts promote tissue contractures during fibrotic diseases. To understand how spontaneous changes in the intracellular calcium concentration, Ca2+, contribute to myofibroblast contraction, we analysed both Ca2+ and subcellular contractio ...