Johan Auwerx, Jun Yong Kim, Wei Chen, Jiujiu Yu, Hong Jiang, Shuo Zhang
Silent information regulator 2 (Sir2) proteins (sirtuins) are nicotinamide adenine dinucleotide-dependent deacetylases that regulate important biological processes. Mammals have seven sirtuins, Sirt1 to Sirt7. Four of them (Sirt4 to Sirt7) have no detectab ...
2011