Combined effects of zoledronate and mechanical stimulation on bone adaptation in an axially loaded mouse tibia
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Motivated by applications in orthopaedic surgery, new constitutive laws for trabecular (or spongious) bone are developed in the framework of continuum mechanics, implemented in a mechanical analysis computer program, validated by a number of in vitro exper ...
CONTEXT: Leptin was initially proposed to be the antiobesity hormone. Now it is realised that leptin is more a signal molecule that communicates nutritional status to the brain, and that it is involved in bone formation by having an antiosteogenic action. ...
Particles generated from orthopedic implants through years of wear play an essential role in the aseptic loosening of a prosthesis. We have investigated the biocompatibility of these orthopedic particles on different osteoblast-like cells representative of ...
OBJECTIVE: We hypothesized that bone mineral density increase following bisphosphonates treatments may be explained by the influence of the drug on the mechanical bone remodeling parameters. BACKGROUND: Patients treated with bisphosphonates continuously in ...
To study bone adaptation to detraining in growing rats, nine weeks-old immature female Wistar rats (n=110) were subjected to treadmill running programs (30 or 60 minutes-a-day) for up to 15 weeks, followed by unrestricted cage activities for the subsequent ...
This article addresses visualization of deformation or shape differences between bones while conventional visualization techniques are often about a single bone such as its 3D reconstruction. Given a pair of bones with a set of corresponding anatomical lan ...
This article addresses visualization of deformation or shape differences between bones while conventional visualization techniques are often about a single bone such as its 3D reconstruction. Given a pair of bones with a set of corresponding anatomical lan ...
Institute of Electrical and Electronics Engineers Computer Society2003
