Chronic woundA chronic wound is a wound that does not heal in an orderly set of stages and in a predictable amount of time the way most wounds do; wounds that do not heal within three months are often considered chronic. Chronic wounds seem to be detained in one or more of the phases of wound healing. For example, chronic wounds often remain in the inflammatory stage for too long. To overcome that stage and jump-start the healing process, a number of factors need to be addressed such as bacterial burden, necrotic tissue, and moisture balance of the whole wound.
Merkel-cell carcinomaMerkel cell carcinoma (MCC) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. It is also known as cutaneous APUDoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, and trabecular carcinoma of the skin. Factors involved in the development of MCC include the Merkel cell polyomavirus (MCPyV or MCV), a weakened immune system, and exposure to ultraviolet radiation.
MelasmaMelasma (also known as chloasma faciei, or the mask of pregnancy when present in pregnant women) is a tan or dark skin discoloration. Melasma is thought to be caused by sun exposure, genetic predisposition, hormone changes, and skin irritation. Although it can affect anyone, it is particularly common in women, especially pregnant women and those who are taking oral or patch contraceptives or hormone replacement therapy medications. The symptoms of melasma are dark, irregular, well-demarcated, hyperpigmented macules to patches.
Graph of a functionIn mathematics, the graph of a function is the set of ordered pairs , where In the common case where and are real numbers, these pairs are Cartesian coordinates of points in two-dimensional space and thus form a subset of this plane. In the case of functions of two variables, that is functions whose domain consists of pairs the graph usually refers to the set of ordered triples where instead of the pairs as in the definition above. This set is a subset of three-dimensional space; for a continuous real-valued function of two real variables, it is a surface.
