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Stem cells are characterized by their dual ability to reproduce themselves (self-renew) and specialize (differentiate), yielding essentially unlimited numbers of daughter cells that can maintain and regenerate tissues. In contrast to their embryonic counte ...
In the domain of regenerative medicine research there are many fronts aimed at increasing our understanding of induced pluripotent, embryonic and adult stem cells. Recently a new front has appeared, stem cell niches, the microenvironment that is a crucial ...
The extracellular matrix (ECM) exerts powerful control over many cellular phenomena, including stem cell differentiation. As such, design and modulation of ECM analogs to ligate specific integrin is a promising approach to control cellular processes in vit ...
Controlling the fate of stem cells in vitro is a key challenge towards using these cells in clinical applications. Adult stem cells (ASC) are known to reside in complex microenvironments called niches in vivo. These niches regulate stem cell fate providing ...
Of the many external factors that affect cell behavior, mechanical cues have been found to be fundamental in modulating a cell’s phenotype. Indeed, merely changing substrate stiffness in monolayer culture systems generates drastically different phenotypes ...
In a recent article M. Colyvan has argued that Quinean forms of scientific realism are faced with an unexpected upshot. Realism concerning a given class of entities, along with this route to realism, can be vindicated by running an indispensability argumen ...
The potential of stem cells in clinics and as a diagnostic tool is still largely unmet, partially due to a lack of in vitro models that efficiently mimic the in vivo stem cell microenvironment—or niche—and thus would allow reproducible propagation of stem ...
This paper describes the concept, design and development process of an interactive and immersive exhibition on state-of-the-art façade technologies for advanced daylighting control. Its aim is to propose an effective, informative and interactive experience ...
Stem cells are characterized by their dual ability to self- renew and differentiate, yielding essentially unlimited numbers of progeny that can replenish tissues with either high turnover such as blood and skin or contribute to the regeneration of organs w ...
Nematodynamics is the orientation dynamics of flowless liquid-crystals. We show how Euler-Poincar, reduction produces a unifying framework for various theories, including Ericksen-Leslie, Luhiller-Rey, and Eringen's micropolar theory. In particular, we sho ...
