Availability heuristicThe availability heuristic, also known as availability bias, is a mental shortcut that relies on immediate examples that come to a given person's mind when evaluating a specific topic, concept, method, or decision. This heuristic, operating on the notion that, if something can be recalled, it must be important, or at least more important than alternative solutions not as readily recalled, is inherently biased toward recently acquired information. The mental availability of an action's consequences is positively related to those consequences' perceived magnitude.
Interprocedural optimizationInterprocedural optimization (IPO) is a collection of compiler techniques used in computer programming to improve performance in programs containing many frequently used functions of small or medium length. IPO differs from other compiler optimizations by analyzing the entire program as opposed to a single function or block of code. IPO seeks to reduce or eliminate duplicate calculations and inefficient use of memory and to simplify iterative sequences such as loops.
EpigeneticsIn biology, epigenetics is the study of stable changes in cell function (known as marks) that do not involve alterations in the DNA sequence. The Greek prefix epi- (ἐπι- "over, outside of, around") in epigenetics implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, and that persist through cellular division.
Total orderIn mathematics, a total order or linear order is a partial order in which any two elements are comparable. That is, a total order is a binary relation on some set , which satisfies the following for all and in : (reflexive). If and then (transitive). If and then (antisymmetric). or (strongly connected, formerly called total). Reflexivity (1.) already follows from connectedness (4.), but is required explicitly by many authors nevertheless, to indicate the kinship to partial orders.
Karnaugh mapThe Karnaugh map (KM or K-map) is a method of simplifying Boolean algebra expressions. Maurice Karnaugh introduced it in 1953 as a refinement of Edward W. Veitch's 1952 Veitch chart, which was a rediscovery of Allan Marquand's 1881 logical diagram aka Marquand diagram but with a focus now set on its utility for switching circuits. Veitch charts are also known as Marquand–Veitch diagrams or, rarely, as Svoboda charts, and Karnaugh maps as Karnaugh–Veitch maps (KV maps).
Boolean algebraIn mathematics and mathematical logic, Boolean algebra is a branch of algebra. It differs from elementary algebra in two ways. First, the values of the variables are the truth values true and false, usually denoted 1 and 0, whereas in elementary algebra the values of the variables are numbers. Second, Boolean algebra uses logical operators such as conjunction (and) denoted as ∧, disjunction (or) denoted as ∨, and the negation (not) denoted as ¬.
DNA microarrayA DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. Each DNA spot contains picomoles (10−12 moles) of a specific DNA sequence, known as probes (or reporters or oligos). These can be a short section of a gene or other DNA element that are used to hybridize a cDNA or cRNA (also called anti-sense RNA) sample (called target) under high-stringency conditions.
DNA sequencingDNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics.
Propositional variableIn mathematical logic, a propositional variable (also called a sentential variable or sentential letter) is an input variable (that can either be true or false) of a truth function. Propositional variables are the basic building-blocks of propositional formulas, used in propositional logic and higher-order logics. Formulas in logic are typically built up recursively from some propositional variables, some number of logical connectives, and some logical quantifiers.
Nucleic acid thermodynamicsNucleic acid thermodynamics is the study of how temperature affects the nucleic acid structure of double-stranded DNA (dsDNA). The melting temperature (Tm) is defined as the temperature at which half of the DNA strands are in the random coil or single-stranded (ssDNA) state. Tm depends on the length of the DNA molecule and its specific nucleotide sequence. DNA, when in a state where its two strands are dissociated (i.e., the dsDNA molecule exists as two independent strands), is referred to as having been denatured by the high temperature.